Cannabidiol solution

Name: Cannabidiol solution
Brand: SIAL

~10 mg/mL in ethanol, analytical standard, for drug analysis

Synonym(s):

CBD

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₃₀O₂

CAS Number:

13956-29-1

Molecular Weight:

314.46

NACRES:

NA.24

PubChem Substance ID:

329769963

UNSPSC Code:

41116107

EC Number:

200-578-6

MDL number:

MFCD00869597

Key Documents

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Product Name

Cannabidiol solution, ~10 mg/mL in ethanol, analytical standard, for drug analysis

InChI key

QHMBSVQNZZTUGM-ZWKOTPCHSA-N

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

SMILES string

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1

assay

≥98.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

concentration

~10 mg/mL in ethanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

suitability

corresponds for H-NMR

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

Quality Level

100

Gene Information

human ... CNR1(1268)

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Show Differences

1 of 4

This Item	C6395	C-045	1089161
Supelco 90899 Cannabidiol solution	Supelco C6395 Cannabidiol solution	Supelco C-045 Cannabidiol solution	USP 1089161 Cannabidiol solution
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) -
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) cannabis testing cannabis testing	application(s) pharmaceutical (small molecules)
grade analytical standard, for drug analysis	grade analytical standard	grade certified reference material	grade -
assay ≥98.5% (HPLC)	assay -	assay -	assay -
format single component solution	format single component solution	format single component solution	format neat
shelf life limited shelf life, expiry date on the label	shelf life -	shelf life -	shelf life -

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Cannabidiol solution may be used for studies regarding the application of cannabidiol for immune-related diseases via studying its immunosuppressive mechanism.[1]

Packaging

ampoule contains 1.2mL solution

pictograms

GHS02,GHS07

signalword

Danger

hcodes

H225,H319

pcodes

P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

57.2 °F - closed cup

flash_point_c

14 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles From Giardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells.

Bruno Gavinho et al.

Frontiers in cellular and infection microbiology, 10, 417-417 (2020-10-20)

Giardia intestinalis is a microaerophilic protozoan that is an important etiologic agent of diarrhea worldwide. There is evidence that under diverse conditions, the parasite is capable of shedding extracellular vesicles (EVs) which modulate the physiopathology of giardiasis. Here we describe

Cannabidiol (CBD) induces functional Tregs in response to low-level T cell activation

Dhital S, et al.

Cellular Immunology, 312, 25-34 (2017)

Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats.

Marcos Hortes N Chagas et al.

Journal of psychopharmacology (Oxford, England), 27(3), 312-316 (2013-01-25)

Cannabidiol (CBD) is one of the main components of Cannabis sativa and has a wide spectrum of action, including effects in the sleep-wake cycle. The objective of this paper is to assess the effects on sleep of acute systemic administration

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin.

R G Pertwee

British journal of pharmacology, 153(2), 199-215 (2007-09-11)

Cannabis sativa is the source of a unique set of compounds known collectively as plant cannabinoids or phytocannabinoids. This review focuses on the manner with which three of these compounds, (-)-trans-delta9-tetrahydrocannabinol (delta9-THC), (-)-cannabidiol (CBD) and (-)-trans-delta9-tetrahydrocannabivarin (delta9-THCV), interact with cannabinoid

Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats.

Alline Cristina Campos et al.

Psychopharmacology, 226(1), 13-24 (2012-09-26)

Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute systemic or intra-dorsal periaqueductal gray (DPAG) administration. However, the effects of CBD repeated administration, and the possible mechanisms involved

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