Yes, both package sizes have a septum cap closure as shown in the image below:
D2438
Dimethyl sulfoxide
sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma
Dimethyl sulfoxide
Synonym(s):
DMSO
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Select a Size
50 ML
RM 938.00
5 X 10 ML
RM 979.00
RM 938.00
Estimated to ship on26 December 2025
About This Item
Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
Beilstein:
506008
EC Number:
MDL number:
UNSPSC Code:
12191502
PubChem Substance ID:
NACRES:
NA.75
Grade:
BioPerformance Certified
Technique(s):
cell culture | hybridoma: suitable
cryopreservation: suitable
cryopreservation: suitable
Bp:
189 °C (lit.)
Vapor pressure:
0.42 mmHg ( 20 °C)
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grade
BioPerformance Certified
Quality Level
Agency
USP XXIV
meets EP testing specifications
meets USP testing specifications
vapor density
2.7 (vs air)
vapor pressure
0.42 mmHg ( 20 °C)
sterility
sterile-filtered
form
liquid
autoignition temp.
573 °F
expl. lim.
42 %, 63 °F
technique(s)
cell culture | hybridoma: suitable
cryopreservation: suitable
impurities
≤0.1% water
color
colorless
refractive index
n20/D 1.479 (lit.)
bp
189 °C (lit.)
mp
16-19 °C (lit.)
solubility
H2O: miscible (completely)
density
1.10 g/mL (lit.)
SMILES string
CS(C)=O
InChI
1S/C2H6OS/c1-4(2)3/h1-2H3
InChI key
IAZDPXIOMUYVGZ-UHFFFAOYSA-N
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1 of 4
This Item | 41640 | 34869 | 472301 |
|---|---|---|---|
| Quality Level 400 | Quality Level 300 | Quality Level 100 | Quality Level 200 |
| grade BioPerformance Certified | grade ACS reagent, puriss. p.a. | grade - | grade ACS reagent |
| technique(s) cell culture | hybridoma: suitable, cryopreservation: suitable | technique(s) - | technique(s) HPLC: suitable | technique(s) - |
| solubility H2O: miscible (completely) | solubility - | solubility - | solubility - |
| form liquid | form liquid | form liquid | form liquid |
| vapor pressure 0.42 mmHg ( 20 °C) | vapor pressure 0.42 mmHg ( 20 °C) | vapor pressure 0.42 mmHg ( 20 °C) | vapor pressure 0.42 mmHg ( 20 °C) |
General description
Dimethyl sulfoxide (DMSO) is an aprotic solvent. Therapeutic and toxic molecules that are not soluble in water are often soluble in DMSO. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. DMSO is used to prepare stock solutions of various molecules and is also used as a control for these molecules. It has been used in cell migration assay for dissolving post-migration cells. BPC-tested DMSO also meets the requirements of biotechnology and tissue engineering applications.
Application
Features and Benefits
Ready-to-use sterile filtered product conveniently packaged in septum screw-capped amber bottles. Meets USP and EP testing requirements
Disclaimer
Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
188.6 °F - closed cup
Flash Point(C)
87 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Articles
Overview of good cell banking practices for cell line cryopreservation purposes.
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For D2438-5X10ML, do they come in glass ampoule or bottle with lid?
1 answer -
Hi, what is the difference between DMSO product# D2438 and D2650? What is Hybri-Max vs. BioPerformance certified and meets USP testing specification?
1 answer-
Both D2438 and D2650 are suitable for cell culture. The D2650 is part of the Hybri-Max™ product line. Hybri-Max products have been tested for use in hybridoma creation and culture. The D2438 is part of the BioPerformance Certified group of products. These products are tested and optimized for use in biological applications. For this product and a number of others, this includes testing to meet USP and EP guidelines. Please see the links below to review a sample Certificate of Analysis for each item.
D2650
https://www.sigmaaldrich.com/product/sigma/d2438#product-documentation
D2438
https://www.sigmaaldrich.com/product/sigma/d2650#product-documentationHelpful?
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Purity grade of the product ?
1 answer-
The purity of this product is listed on the lot specific Certificate of Analysis. Please navigate to the DOCUMENTATION section of the Product Detail Page to access a Certificate:
https://www.sigmaaldrich.com/product/sigma/d2438#product-documentationHelpful?
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El DMSO es sensible a la luz, hay que tomar alguna precaución al respecto?
1 answer-
This product is packaged in amber glass and is protected from light. The 10 mL size is packaged in a sealed ampule. Once opened, any content that is not used should also be stored in amber glass. For long term storage, the material may also be stored under inert gas to preserve the shelf life. Note that this material has a tendency to absorb water. Containers should be tightly sealed.
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what are the storing conditions?
1 answer-
This product is stored at room temperature. Store in a well-ventilated place. Keep cool. Please see the Material Safety Data Sheet for more information: https://www.sigmaaldrich.com/sds/sigma/d2438.
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What is the difference between products D2438 and D8418?
1 answer-
The D2438 is a BioPerformance Certified grade product suitable for cell culture, hybridoma creation, and cryopreservation. It is intended for research use only but does meet USP and EP testing requirements. The D8418 is a molecular biology-grade product suitable for DNA sequencing, PCR, and transfection. It has been tested for RNAse and DNAse. The products can be selected based on the application.
Please view the sample Certificate of Analysis for each product to see the testing specifications associated with that item:
https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/fluka/pdf/PDF734068.pdf
https://www.sigmaaldrich.com/coa/SIGMA/D2438/RNBL8837Helpful?
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What is the basis for the endotoxin specification for Dimethyl sulfoxide (DMSO)?
1 answer-
The industry standard for 'endotoxin free' is less than 1 EU/mL.
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Dimethyl sulfoxide (DMSO) should be a liquid. Why did it arrive as a solid?
1 answer-
DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.
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What is the molarity of DMSO?
1 answer-
DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.
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Where does DMSO come from?
1 answer-
DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.
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