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EHU135461

MISSION® esiRNA

targeting human INSL3

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UNSPSC Code:
41105324
NACRES:
NA.51

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description

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Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TCAGTGGCTGTACCCAACAAGACCTGCTGACCCTCTGTCCCTACTGATTCCTCCTTGGGTGCAGCCTCAGAGTGGCCTGAGGCCCAGAGGGTCTGGTCTGGTGAGCTCCTGAGGCCACACAGCACCATAAAGTCTCGCATCTACAGGCCTTTGATTACCTCCTGGGATGGGTGCTCACTATCTACCCCAGACCAATGCCACCTGCAGCCTGTGGAGTCAACTGCAGAATAAATCACACCCTAGCCCTGGCTTGGAGGATCCCCGCTTTCACAGATGCTGGACACTGACAGCCAAATGTCCTCAC

Ensembl | human accession no.

ENSG00000105639

NCBI accession no.

NM_000215

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... INSL3(3640), JAK3(3718)

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MISSION® esiRNA targeting human INSL3

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EHU135461

MISSION® esiRNA

MISSION® esiRNA targeting human ITGB3, RP11-290H9.2

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EHU051661

MISSION® esiRNA

MISSION® esiRNA targeting human INSL5

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EHU038671

MISSION® esiRNA

MISSION® esiRNA targeting human ZC3HAV1

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EHU081401

MISSION® esiRNA

Gene Information

human ... INSL3(3640), JAK3(3718)

Gene Information

human ... ITGB3(3690), ITGB3(3690)

Gene Information

human ... INSL5(10022), INSL5(10022)

Gene Information

human ... ZC3HAV1(56829), ZC3HAV1(56829)

esiRNA cDNA target sequence

TCAGTGGCTGTACCCAACAAGACCTGCTGACCCTCTGTCCCTACTGATTCCTCCTTGGGTGCAGCCTCAGAGTGGCCTGAGGCCCAGAGGGTCTGGTCTGGTGAGCTCCTGAGGCCACACAGCACCATAAAGTCTCGCATCTACAGGCCTTTGATTACCTCCTGGGATGGGTGCTCACTATCTACCCCAGACCAATGCCACCTGCAGCCTGTGGAGTCAACTGCAGAATAAATCACACCCTAGCCCTGGCTTGGAGGATCCCCGCTTTCACAGATGCTGGACACTGACAGCCAAATGTCCTCAC

esiRNA cDNA target sequence

CAGGCATTGTCCAGCCTAATGACGGGCAGTGTCATGTTGGTAGTGACAATCATTACTCTGCCTCCACTACCATGGATTATCCCTCTTTGGGGCTGATGACTGAGAAGCTATCCCAGAAAAACATCAATTTGATCTTTGCAGTGACTGAAAATGTAGTCAATCTCTATCAGAACTATAGTGAGCTCATCCCAGGGACCACAGTTGGGGTTCTGTCCATGGATTCCAGCAATGTCCTCCAGCTCATTGTTGATGCTTATGGGAAAATCCGTTCTAAAGTAGAGCTGGAAGTGCGTGACCTCCCTGAAGAGTTGTCTCTATCCTTCAATGCCACCTGCCTCAACAATGAGGTCATCCCTGGCCTCAAGTCTTGTATGGGACTCAAGATTGGAGACACGGTGAGC

esiRNA cDNA target sequence

CCTTCCAGCTCCCACATAAACGTGAGTTTTCTGAGGAAAATCCAGCGCAAAACCTTCCGAAGGTGGATGCCTCAGGGGAAGACCGTCTTTGGGGTGGACAGATGCCCACTGAAGAGCTTTGGAAGTCAAAGAAGCATTCAGTGATGTCAAGACAAGATTTACAAACTTTGTGTTGCACTGATGGCTGTTCCATGACTGATTTGAGTGCTCTTTGCTAAGACAAGAGCAAATACCCAATGGGTGGCAGAGCTTTATCACATGTTTAATTACAGTGTTTTACTGCCTGGTAGAACACTAATATTGTGTTATTAAAATGATGGCTTTTGGGTAGGCAAAACTTCTTTTCTAAAAGGTATAGCTGAGCGGTTGAAACCACAGTGATCTCTATTTTCTCCCTTTGCCAAGGTTA

esiRNA cDNA target sequence

TGGGCACAGCTGTAACTGAAGACCTAATGAAGTAGTCAGATGCTTACAACTATTTATAATGCATCAATTTGAACTTAGAAGGTAGGAGATCAGATCATATGTGGGAAAATGTAAAAGCAGGGATATCAGTGGGCATTAGAATAAAAACTAGGGATACAATAACTTCTTTGCATATGACAATACTTATTTGTATATAAGAGAAAGAACGAAATAACCTTTATTGAAATAAAGATACTATGCAAGAAAATGTACAGTTGTCGAAGTGGAGAAAATGAGGATATATTCTTGCAGACGAGCTATAGGTCATACATGAATGTCTAGTGAGACATTCAAAATTCGTATAGGGTGCAGAGTAATTTCTTATTGTGAGGAACTGTCCAATGTATTGCAAGATGTTCTGCATACTTGGCTCTCACATACTAAATGCTAGTAGCGCCCC

Ensembl | human accession no.

ENSG00000105639

Ensembl | human accession no.

ENSG00000056345

Ensembl | human accession no.

ENSG00000172410

Ensembl | human accession no.

ENSG00000105939

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

NCBI accession no.

NM_000215

NCBI accession no.

NM_000212

NCBI accession no.

NM_005478

NCBI accession no.

NM_020119

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Nina A Sibbesen et al.
Oncotarget, 6(24), 20555-20569 (2015-08-06)
Aberrant activation of Janus kinase-3 (Jak3) and its key down-stream effectors, Signal Transducer and Activator of Transcription-3 (STAT3) and STAT5, is a key feature of malignant transformation in cutaneous T-cell lymphoma (CTCL). However, it remains only partially understood how Jak3/STAT

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