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EHU159081

MISSION® esiRNA

targeting human SHMT1

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UNSPSC Code:
41105324
NACRES:
NA.51

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description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TACTCTCCCTGGGCTTTCCTCCGCCTTGCTGCAACAGAGAGGAAATGCCCATGTCCACAGCTTGTACACACTGCCCCCTCACTATCTTGTTATCCAGTGGCATGCCAAAGGAGAACTGAATTAGCTTCTGAGGCTTCTGCTGTAAATCAGAAGTGTATGTTAGTCAAGAGTAAACAAGATGCACCCAGTATGGTGGGAGGGTTTTGCTGTCAGTAGCTCAAAGTATGGTGTAGAAATGGCCTCCTCCCTCCATCCTGGGAAGTCCCAGTCCCATCCTGGTGTGAGAATCAACCAGGCTTTCCTGCTCCACCTGAGATAACCAACTCCCTCCCGT

Ensembl | human accession no.

ENSG00000176974

NCBI accession no.

NM_148918

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... SHMT1(6470), SHMT1(6470)

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MISSION® esiRNA targeting human SHMT1

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MISSION® esiRNA targeting human SHMT2

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MISSION® esiRNA targeting human SI

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MISSION® esiRNA targeting human EHMT1

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esiRNA cDNA target sequence

TACTCTCCCTGGGCTTTCCTCCGCCTTGCTGCAACAGAGAGGAAATGCCCATGTCCACAGCTTGTACACACTGCCCCCTCACTATCTTGTTATCCAGTGGCATGCCAAAGGAGAACTGAATTAGCTTCTGAGGCTTCTGCTGTAAATCAGAAGTGTATGTTAGTCAAGAGTAAACAAGATGCACCCAGTATGGTGGGAGGGTTTTGCTGTCAGTAGCTCAAAGTATGGTGTAGAAATGGCCTCCTCCCTCCATCCTGGGAAGTCCCAGTCCCATCCTGGTGTGAGAATCAACCAGGCTTTCCTGCTCCACCTGAGATAACCAACTCCCTCCCGT

esiRNA cDNA target sequence

GGGGTCAACATTGGCTTAGAGGTGAAGAGCAAGACTGCCAAGCTCCAGGATTTCAAATCCTTCCTGCTTAAGGACTCAGAAACAAGTCAGCGTCTGGCCAACCTCAGGCAACGGGTGGAGCAGTTTGCCAGGGCCTTCCCCATGCCTGGTTTTGATGAGCATTGAAGGCACCTGGGAAATGAGGCCCACAGACTCAAAGTTACTCTCCTTCCCCCTACCTGGGCCAGTGAAATAGAAAGCCTTTCTATTTTTTGGTGCGGGAGGGAAGACCTCTCACTTAGGGCAAGAGCCAGGTATAGTCTCCCTTCCCAGAATTTGTAACTGAGAAGATCTTTTCTTTTTCCTTTTTTTGGTAACAAGACTTAGAAGGAGGGCCCAGGCACTTTCTGTTTGAACCCCTGTCATGA

esiRNA cDNA target sequence

ACCAGCAATGCCAGCATATTGGAATCTTGGATTCCAACTAAGTCGCTGGAATTATAAGTCACTAGATGTAGTGAAAGAAGTGGTAAGGAGAAACCGGGAAGCTGGCATACCATTTGATACACAGGTCACTGATATTGACTACATGGAAGACAAGAAAGACTTTACTTATGATCAAGTTGCGTTTAACGGACTCCCTCAATTTGTGCAAGATTTGCATGACCATGGACAGAAATATGTCATCATCTTGGACCCTGCAATTTCCATAGGTCGACGTGCCAATGGAACAACATATGCAACCTATGAGAGGGGAAACACACAACATGTGTGGATAAATGAGTCAGATGGAAGTACACCAATTATTGGAGAGGTATGGCCAGGATTAACAGTATACCCTGATTTCACTAACCCAAACTGCATTGATTGGTG

esiRNA cDNA target sequence

CTGAGTTCGGAATCCAGCATTAAGAAGAAATTTCTCAAGAGGAAAGGAAAGACCGACAGTCCCTGGATCAAGCCAGCCAGGAAAAGGAGGCGGAGAAGTAGAAAGAAGCCCAGCGGTGCCCTCGGTTCTGAGTCGTATAAGTCATCTGCAGGAAGCGCTGAGCAGACGGCACCAGGAGACAGCACAGGGTACATGGAAGTTTCTCTGGACTCCCTGGATCTCCGAGTCAAAGGAATTCTGTCTTCACAAGCAGAAGGGTTGGCCAACGGTCCAGATGTGCTGGAGACAGACGGCCTCCAGGAAGTGCCTCTCTGCAGCTGCCGGATGGAAACACCGAAGAGTCGAGAGATCACCACACTGGCCAACAACCAGTGCATGGCTACAGAGAGCGTGGACCATGAATT

Ensembl | human accession no.

ENSG00000176974

Ensembl | human accession no.

ENSG00000182199

Ensembl | human accession no.

ENSG00000090402

Ensembl | human accession no.

ENSG00000181090

Gene Information

human ... SHMT1(6470), SHMT1(6470)

Gene Information

human ... SHMT2(6472), SHMT2(6472)

Gene Information

human ... SI(6476), SI(6476)

Gene Information

human ... EHMT1(79813), EHMT1(79813)

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

NCBI accession no.

NM_148918

NCBI accession no.

NM_005412

NCBI accession no.

NM_001041

NCBI accession no.

NM_024757

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Recep Nigdelioglu et al.
The Journal of biological chemistry, 291(53), 27239-27251 (2016-11-12)
TGF-β promotes excessive collagen deposition in fibrotic diseases such as idiopathic pulmonary fibrosis (IPF). The amino acid composition of collagen is unique due to its high (33%) glycine content. Here, we report that TGF-β induces expression of glycolytic genes and

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