M9191
Microsomes from Liver, Pooled
from rat(Sprague-Dawley), female
Synonym(s):
lab equipment accessory
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biological source
rat (Sprague-Dawley)
Quality Level
form
liquid
specific activity
≥20 units/mg protein, pH 7.4, 37 °C
packaging
vial of ~10 mg
shipped in
dry ice
storage temp.
−70°C
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This Item | M9441 | M0692 | M9566 |
|---|---|---|---|
| specific activity ≥20 units/mg protein, pH 7.4, 37 °C | specific activity - | specific activity - | specific activity - |
| biological source rat (Sprague-Dawley) | biological source mouse (CD-1) | biological source human female | biological source mouse (CD-1) |
| form liquid | form liquid | form liquid | form liquid |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
| storage temp. −70°C | storage temp. −70°C | storage temp. −70°C | storage temp. −70°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
Biochem/physiol Actions
Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.
Source of drug metabolizing enzymes, including cytochrome P-450.
Other Notes
One unit will reduce 1 nanomole of cytochrome C per minute at pH 7.4 at 37 deg C.
7-ethoxyresorufin O-deethylase activity: One unit will hydroxylate 1.0 picomole paclitaxel per minute at pH 7.4 at 37 deg C.
7-ethoxyresorufin O-deethylase activity: One unit will hydroxylate 1.0 picomole paclitaxel per minute at pH 7.4 at 37 deg C.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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