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Merck

O7125

L-Ornithine L-aspartate salt

≥98% (TLC)

Synonym(s):

(S)-2,5-Diaminopentanoic acid L-aspartate salt

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About This Item

Empirical Formula (Hill Notation):
C9H19N3O6
CAS Number:
3230-94-2
Molecular Weight:
265.26
NACRES:
NA.26
PubChem Substance ID:
329818920
UNSPSC Code:
12352209
EC Number:
221-772-7
MDL number:
MFCD00058084

Key Documents

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Product Name

L-Ornithine L-aspartate salt, powder

InChI key

IXUZXIMQZIMPSQ-ZBRNBAAYSA-N

InChI

1S/C5H12N2O2.C4H7NO4/c6-3-1-2-4(7)5(8)9;5-2(4(8)9)1-3(6)7/h4H,1-3,6-7H2,(H,8,9);2H,1,5H2,(H,6,7)(H,8,9)/t4-;2-/m00/s1

SMILES string

NCCC[C@H](N)C(O)=O.N[C@@H](CC(O)=O)C(O)=O

assay

≥98% (TLC)

form

powder

color

white to off-white

storage temp.

2-8°C

Quality Level

200

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This Item
O2375O438675490
L-Ornithine L-aspartate salt powder

Sigma-Aldrich

O7125

L-Ornithine L-aspartate salt

L-Ornithine monohydrochloride ≥99%

Sigma-Aldrich

O2375

L-Ornithine monohydrochloride

L-Ornithine monohydrochloride BioXtra, ≥99%

Sigma-Aldrich

O4386

L-Ornithine monohydrochloride

DL-Ornithine monohydrochloride ≥99.0% (AT)

Sigma-Aldrich

75490

DL-Ornithine monohydrochloride

form

powder

form

powder

form

powder

form

powder

assay

≥98% (TLC)

assay

≥99%

assay

≥99%

assay

≥99.0% (AT)

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

color

white to off-white

color

white

color

white

color

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

Biochem/physiol Actions

L-Ornithine L-aspartate is a metabolite of arginine degradation by arginase. It has been shown to reduce blood ammonia concentrations by increasing ammoniadetoxification in the muscle and reducing the severity of hepatic encephalopathy in cirrhosis.

Other Notes

Product of arginine degradation by arginase

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000456907
0000456907
0000369173
0000369173
SLBW4848

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[Study on L-Ornithine-L-Aspartate in the treatment of acute-on-chronic liver failure].
Cui-ping Liu et al.
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 19(1), 63-64 (2011-01-29)
[New approach to diagnostics and correction of portohepatic hemodynamics in patients with chronic liver diseases].
S Iu Ermolov et al.
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (4)(4), 82-87 (2008-04-16)
Irfan Ahmad et al.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 18(11), 684-687 (2008-11-06)
To determine the efficacy of L-ornithine-L-aspartate in treatment of hepatic encephalopathy. Randomized, placebo-controlled trial. Department of Gastroenterology and Hepatology, Sheikh Zayed Hospital, Lahore, from February to August 2005. Cirrhotic patients with hyperammonemia and overt hepatic encephalopathy were enrolled. Eighty patients
[Hepatic encephalopathy. L-ornithine-L-aspartate stimulate detoxification capacity of the liver].
Abdol A Ameri
MMW Fortschritte der Medizin, 152(22), 42-43 (2010-07-02)
Takeyori Saheki et al.
Scientific reports, 9(1), 4179-4179 (2019-03-14)
Previous studies using citrin/mitochondrial glycerol-3-phosphate (G3P) dehydrogenase (mGPD) double-knockout mice have demonstrated that increased dietary protein reduces the extent of carbohydrate-induced hyperammonemia observed in these mice. This study aimed to further elucidate the mechanisms of this effect. Specific amino acids
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