850356P

4ME 16:0 PC

Avanti Research^™ - A Croda Brand

• Synonym(s): 1,2-Diphytanoyl-3-sn-phosphatidylcholine, 1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphocholine; PC(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me)), DPhPC, Diphytanoylphosphatidylcholine
• Empirical Formula (Hill Notation): C₄₈H₉₆NO₈P
• CAS Number: 207131-40-6
• Molecular Weight: 846.25
• MDL number: MFCD00674308
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• description: 1,2-diphytanoyl-sn-glycero-3-phosphocholine
• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 200 mg ((850356P-200MG)); pkg of 1 × 25 mg ((850356P-25MG)); pkg of 1 × 500 mg ((850356P-500MG))
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)=O
• InChI: 1S/C48H96NO8P/c1-38(2)20-14-22-40(5)24-16-26-42(7)28-18-30-44(9)34-47(50)54-36-46(37-56-58(52,53)55-33-32-49(11,12)13)57-48(51)35-45(10)31-19-29-43(8)27-17-25-41(6)23-15-21-39(3)4/h38-46H,14-37H2,1-13H3/t40?,41?,42?,43?,44?,45?,46-/m1/s1
• InChI key: UKDDQGWMHWQMBI-SOFRWFQSSA-N

Description

General description

Lipids containing diphytanoyl fatty acid chains have been used to produce stable planar lipid membranes (see References). Diphytanoyl phosphatidylcholine does not exhibit a detectable gel to liquid crystalline phase transition from -120°C to +120°C.The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis.

Application

4ME 16:0 PC has been used:

• in the electrophysiology studies of chloride channel[1]
• for the generation of Droplet-Hydrogel Bilayer (DHB), which is used for protein reconstitution studies[2]
• for the generation of lipid bilayers for single channel and ion selectivity measurements studies[3]

Biochem/physiol Actions

1,2-diphytanoyl-sn-glycero-3-phosphocholine (4ME 16:0 PC) or DPhPC has choline head groups and favors formation of membrane lipid bilayer. It displays low permeability towards ions and water. DPhPC is majorly used lipid for electrophysiological measurements and ion conductivity studies.[4]

Packaging

20 mL Clear Glass Screw Cap Vial (850356P-200mg)

30 mL Amber Wide Mouth Bottle with Screw Cap (850356P-500mg)

5 mL Clear Glass Sealed Ampule (850356P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3