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Merck

1.10110

2-[4-(2-Hydroxyethyl)-1-piperazinyl]-ethanesulfonic acid

HEPES EMPROVE® EXPERT

Synonym(s):

HEPES, 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid)

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About This Item

Empirical Formula (Hill Notation):
C8H18N2O4S
CAS Number:
7365-45-9
Molecular Weight:
238.30
Beilstein:
883043
MDL number:
MFCD00006158
UNSPSC Code:
12161703
EC Index Number:
230-907-9

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Quality Level

500

product line

EMPROVE® EXPERT

potency

>2000 mg/kg LD50, oral (Rat)

feature

RNase and DNase free

technique(s)

API processing | cocrystal formation: suitable

pH

5.0-5.5 (20 °C, 100 g/L in H2O)

useful pH range

6.8-8.2

pKa (25 °C)

7.5

mp

212.6 °C

solubility

703.6 g/L

density

1.44 g/cm3 at 20 °C

bulk density

560 kg/m3

storage temp.

2-25°C

SMILES string

OCCN1CCN(CC1)CCS(O)(=O)=O

InChI

1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)

InChI key

JKMHFZQWWAIEOD-UHFFFAOYSA-N

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This Item
H3537H0887H0887
2-[4-(2-Hydroxyethyl)-1-piperazinyl]-ethanesulfonic acid HEPES EMPROVE® EXPERT

SAFC

1.10110

2-[4-(2-Hydroxyethyl)-1-piperazinyl]-ethanesulfonic acid

HEPES solution BioPerformance Certified, 1 M, suitable for cell culture, 0.2 μm filtered

Sigma-Aldrich

H3537

HEPES solution

HEPES solution 1 M, pH 7.0-7.6, sterile-filtered, BioReagent, suitable for cell culture

Sigma-Aldrich

H0887

HEPES solution

HEPES solution 1 M, pH 7.0-7.6, sterile-filtered, BioReagent, suitable for cell culture

Sigma-Aldrich

H0887

HEPES solution

technique(s)

API processing | cocrystal formation: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

solubility

703.6 g/L

solubility

-

solubility

-

solubility

-

bulk density

560 kg/m3

bulk density

-

bulk density

-

bulk density

-

density

1.44 g/cm3 at 20 °C

density

-

density

1.1 g/cm3

density

1.1 g/cm3

product line

EMPROVE® EXPERT

product line

-

product line

BioReagent, BioXtra

product line

BioReagent, BioXtra

potency

>2000 mg/kg LD50, oral (Rat)

potency

-

potency

-

potency

-

General description

Our SAFC® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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