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Merck

A0278

L-Ascorbic acid

reagent grade

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

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About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
200-066-2
Beilstein/REAXYS Number:
84272
MDL number:

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Product Name

L-Ascorbic acid, reagent grade

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

biological source

synthetic

grade

reagent grade

assay

≥98% (with Iodine, titration)

form

powder

technique(s)

HPLC: suitable

color

white to light yellow

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 50 mg/mL

Quality Level

Gene Information

human ... SLC23A2(9962)

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This Item
A750625556433034
grade

reagent grade

grade

reagent grade

grade

ACS reagent

grade

ACS reagent, puriss. p.a.

assay

≥98% (with Iodine, titration)

assay

≥98% ( with iodine, titration)

assay

≥99%

assay

99.7-100.5% (oxidimetric)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

crystalline

form

crystals or granules, powder or chunks

form

solid

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

2.1-2.6 (20 °C, 5%)

solubility

water: soluble 50 mg/mL

solubility

water: soluble 50 mg/mL

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 176 g/L at 20 °C

Application

L-Ascorbic acid has been used as a standard in high performance liquid chromatography (HPLC) for quantification of L-ascorbic acid.[1]
L-Ascorbic acid may be used as standard in assay for erythrocyte hemolysis mediated by peroxyl free radicals.[2] It may be used for the reduction of graphene oxide sheets.[3]

Biochem/physiol Actions

L-Ascorbic acid is an anti-oxidant. L-Ascorbic acid (vitamin C) is important for many enzymatic reactions for maintaining prosthetic metal ions in their reduced forms (for example, Fe2+, Cu+). It protects tissues from oxidative damage by scavenging free radicals.[4] It has mild reductive ability and nontoxic property. It is commonly employed reductant in the laboratory.[3] Colorimetric determination of ascorbic acid in plasma using acid phosphotungstate has been reported.[5]
L-ascorbic acid modified poly(ester urethane)s might facilitate soft tissue regeneration.[6] It also helps in increasing iron absorption by tissues. In addition, it aids in tyrosine metabolism and microsomal drug metabolism.[7]

Disclaimer

May darken in storage.

General description

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates.[7] It is a water-soluble vitamin.[8]

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Synthesis and characterization of cycloaliphatic hydrophilic polyurethanes, modified with L-ascorbic acid, as materials for soft tissue regeneration
Kucinska-Lipka J, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 75(3), 671-681 (2017)
Dehydrofreezing of pineapple
Ramallo LA and Mascheroni RH
Journal of Food Engineering, 99(3), 269-275 (2010)
Jk Psc Quick Review for Medical Officers: A Useful Manual For NEET, AIIMS and PGI Md/Ms. Entrance Exams (2018)
Gemma Rush et al.
Parasitology, 146(9), 1184-1187 (2019-03-13)
Bovine trichomoniasis is a notifiable, reproductive disease of cattle caused by the parasite Tritrichomonas foetus. Culturing with modified Diamond's medium (MDM) is required to increase the low number of organisms received from a preputial sample, but is limited in application
Total phenols, ascorbic acid, β-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities.
Barros L, et al.
Food Chemistry, 103(2), 413-419 (2007)

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