1237382

Epirubicin hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 4′-Epidoxorubicin hydrochloride, Epidoxorubicin hydrochloride
• Empirical Formula (Hill Notation): C₂₇H₂₉NO₁₁ · HCl
• CAS Number: 56390-09-1
• Molecular Weight: 579.98
• NACRES: NA.24
• PubChem Substance ID: 329749729
• UNSPSC Code: 41116107
• MDL number: MFCD00941448

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: epirubicin
• manufacturer/tradename: USP
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
• InChI: 1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22-,27-;/m0./s1
• InChI key: MWWSFMDVAYGXBV-FGBSZODSSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Epirubicin hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Doxorubicin Hydrochloride
• Doxorubicin Hydrochloride for Injection
• Doxorubicin Hydrochloride Injection
• Epirubicin Hydrochloride
• Epirubicin Hydrochloride Injection

Biochem/physiol Actions

Cell-permeable anthracycline antitumor antibiotic. Antineoplastic. A stereoisomer of doxorubicin that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Codes: H302,H340,H350,H360
• Precautionary Statements: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable