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Merck

388513

5,8-Dihydroxy-1,4-naphthoquinone

technical grade

Synonym(s):

Naphthazarin

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1 G

PLN 1,310.00

PLN 1,310.00


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About This Item

Empirical Formula (Hill Notation):
C10H6O4
CAS Number:
Molecular Weight:
190.15
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
207-495-4
Beilstein/REAXYS Number:
880561
MDL number:

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Product Name

5,8-Dihydroxy-1,4-naphthoquinone, technical grade

InChI key

RQNVIKXOOKXAJQ-UHFFFAOYSA-N

InChI

1S/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H

SMILES string

Oc1ccc(O)c2C(=O)C=CC(=O)c12

grade

technical grade

mp

220-230 °C (lit.)

Quality Level

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Régis Millet et al.
Journal of medicinal chemistry, 48(22), 7024-7039 (2005-10-28)
The human selenoprotein thioredoxin reductase is involved in antioxidant defense and DNA synthesis. As increased thioredoxin reductase levels are associated with drug sensitivity to cisplatin and drug resistance in tumor cells, this enzyme represents a promising target for the development
Brígida R Pinho et al.
PloS one, 6(8), e24098-e24098 (2011-09-03)
The search of new anti-inflammatory drugs has been a current preoccupation, due to the need of effective drugs, with less adverse reactions than those used nowadays. Several naphthoquinones (plumbagin, naphthazarin, juglone, menadione, diosquinone and 1,4-naphthoquinone), plus p-hydroquinone and p-benzoquinone were
Gulseren Pekin et al.
Planta medica, 73(3), 267-272 (2007-02-24)
The quantification of free and total alkannins in 13 endemic Anatolian Alkanna species is described for the first time. Extraction of the samples was performed by sonication with hexane, followed by hydrolysis in 1 N NaOH. For analysis, a new
Angela N Kuntz et al.
PLoS medicine, 4(6), e206-e206 (2007-06-21)
Schistosomiasis--infection with helminth parasites in the genus Schistosoma, including S. mansoni--is a widespread, devastating tropical disease affecting more than 200 million people. No vaccine is available, and praziquantel, the only drug extensively utilized, is currently administered more than 100 million
Eiríkur Stephensen et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 133(3), 435-442 (2002-10-16)
In fish, as in other aerobic organisms, glutathione and glutathione-related enzymes are important components in the defences against oxidative stress. To study if hepatic glutathione levels and/or activities of glutathione-related enzymes can act as indicators of oxidative stress in fish

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