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Merck

925802

Silk fibroin

average mol wt 100 kDa (water soluble)

Synonym(s):

SilMA, Silk fibroin

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1 G

PLN 460.00

PLN 460.00


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About This Item

NACRES:
NA.23
UNSPSC Code:
12162002

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Product Name

Silk fibroin, average mol wt 100 kDa (water soluble)

mol wt

average mol wt 100 kDa (water soluble)

color

white to off-white

pH

6-8 (2% in water, when dissolved in water)

Quality Level

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515492592681280
mol wt

average mol wt 100 kDa (water soluble)

mol wt

avg mol wt 100 kDa

mol wt

average mol wt >10000

mol wt

8500-11500

color

white to off-white

color

-

color

white to off-white

color

-

pH

6-8 (2% in water, when dissolved in water)

pH

-

pH

6-7 ( in water)

pH

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

General description

Silk is a natural polymer composed of two proteins - fibroin and sericin.
Silk fibroin is used in biomedical applications due to its enhanced biocompatibility and biodegradability.

Silk fibroin (SF) demonstrates enhanced strength and stability compared to other common natural polymers due to its unique features including;
  • amphiphilicity
  • hydrophobicity
  • substantial hydrogen bonding
  • intrinsic low viscosity
  • high protein crystallinity by ß-sheet crystals.

Packaging

1 g in glass bottle

Application

SF is a versatile material, that finds itself in multiple types of scaffolds, with extensive uses in inkjet, extrusion-based, laser-assisted, and DLP bioprinting tissue engineering applications.

Storage Class

11 - Combustible Solids

wgk

WGK 3


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Xiaohui Zhang et al.
Advanced drug delivery reviews, 61(12), 988-1006 (2009-08-01)
Electrospinning is a versatile technique that enables the development of nanofiber-based biomaterial scaffolds. Scaffolds can be generated that are useful for tissue engineering and regenerative medicine since they mimic the nanoscale properties of certain fibrous components of the native extracellular
Precisely printable and biocompatible silk fibroin bioink for digital light processing 3D printing.
Kim S H, et al.
Nature Communications, 9, 1620-1620 (2018)
Heesun Hong et al.
Biomaterials, 232, 119679-119679 (2019-12-23)
Three-dimensional printing with Digital Lighting Processing (DLP) printer has come into the new wave in the tissue engineering for regenerative medicine. Especially for the clinical application, it needs to develop of bio-ink with biocompatibility, biodegradability and printability. Therefore, we demonstrated
Soon Hee Kim et al.
Nature communications, 9(1), 1620-1620 (2018-04-26)
Although three-dimensional (3D) bioprinting technology has gained much attention in the field of tissue engineering, there are still several significant engineering challenges to overcome, including lack of bioink with biocompatibility and printability. Here, we show a bioink created from silk

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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