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Merck

8.17061

TWEEN® 80 (Polysorbate)

EMPROVE® ESSENTIAL, Ph. Eur., JP, NF

Synonym(s):

TWEEN® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

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1 L

PLN 400.00

2.5 L

PLN 795.00

25 KG

PLN 4,400.00

50 KG

PLN 8,180.00

PLN 400.00


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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352104
EC Index Number:
500-019-9

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Agency

JP
NF
Ph. Eur.

Quality Level

vapor pressure

<1.33 hPa

product line

EMPROVE® ESSENTIAL

form

viscous liquid

technique(s)

API processing | nano-milling: suitable

pH

5-7 (20 °C, 50 g/L in H2O)

kinematic viscosity

300-500 cSt(25 °C)

bp

>100 °C/1013 hPa

transition temp

flash point >149 °C

density

1.07 g/cm3 at 25 °C

application(s)

liquid formulation
ophthalmics
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement

storage temp.

15-25°C

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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1 of 4

This Item
1.37171PHR37901547969
application(s)

liquid formulation
ophthalmics
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement

application(s)

liquid formulation
parenterals
pharmaceutical

application(s)

pharmaceutical

application(s)

pharmaceutical (small molecule)

technique(s)

API processing | nano-milling: suitable

technique(s)

-

technique(s)

-

technique(s)

-

agency

JP, Ph. Eur., NF

agency

ChP, JP, NF, Ph. Eur.

agency

traceable to USP 1547969

agency

-

form

viscous liquid

form

liquid

form

-

form

-

product line

EMPROVE® ESSENTIAL

product line

EMPROVE® EXPERT

product line

-

product line

-

density

1.07 g/cm3 at 25 °C

density

1.07 g/cm3 at 25 °C

density

-

density

-

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polysorbate 80 is used as surfactant in a variety of liquid formulations and acts e.g. as emulsifying, solubilizing and wetting agent.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

>235.4 °F - closed cup

Flash Point(C)

> 113 °C - closed cup


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Articles

Dowiedz się więcej o naszej ofercie pożywek do badania mikrobiologicznego produktów niesterylnych, w pełni zgodnych ze zharmonizowaną Farmakopeą.

Learn more about our culture media portfolio for microbial examination of non-sterile products, fully compliant with the harmonized Pharmacopoeia.

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

Related Content

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

This page summarizes key considerations related to regulatory expectations for biomanufacturing including chemicals and polymeric materials. For chemicals, topics include nitrosamines and elemental impurities, and for polymeric materials such as filters and single-use assemblies, the focus is qualification and extractable and leachable testing.

Culture Media for compendial methods

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