AB10522

Anti-Neuropilin-2 Antibody

serum, from rabbit

• Synonym(s): Vascular endothelial cell growth factor 165 receptor 2, neuropilin 2, receptor for VEGF165 and semaphorins class 3, vascular endothelial growth factor-165 receptor 2
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: mouse
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotype: IgG
• NCBI accession no.: NP_110496.1
• UniProt accession no.: O35276
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... NRP2(8828)

Description

General description

130 kDa

There are two forms of Neuropilin: Neuropilin-1 and Neuropilin-2. These are non–tyrosine kinase receptors that bind to VEGF and semaphorins (SEMA3A, SEMA3B, and SEMA3F) and play an important role in the critical functioning of the nervous system. Neuropilin-2 is expressed in tumor cells, and mature and developing endothelial cells and vascular smooth muscle cells. This expression has been associated with tumor angiogenesis and progression.

Immunogen

His-tagged partial recombinant rat Neuropilin-2 protein.

Application

Detect Neuropilin-2 using this Anti-Neuropilin-2 Antibody validated for use in WB, IH, IP & IF.

Biochem/physiol Actions

This antibody recognizes Neuropilin-2.

Physical form

Unpurified Rabbit Serum containing 0.05% Sodium Azide.

Analysis Note

Control
Mouse P1 brain tissue lysate

Evaluated by Western Blot in mouse P1 brain tissue lysate.

Western Blot Analysis: 1:1000 dilution of this antibody detected Neuropilin-2 on 10 µg of mouse P1 brain tissue lysate.

Other Notes

Replaces: AB9160

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1