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Merck

L5750

Sodium dodecyl sulfate

greener alternative

92.5-100.5% based on total alkyl sulfate content basis

Synonym(s):

Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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100 G

PLN 141.00

500 G

PLN 294.00

1 KG

PLN 497.00

5 KG

PLN 1,980.00

PLN 141.00


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About This Item

Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
Molecular Weight:
288.38
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39093306
UNSPSC Code:
12161900
EC Number:
205-788-1
MDL number:
Beilstein/REAXYS Number:
3599286

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Product Name

Sodium dodecyl sulfate, 92.5-100.5% based on total alkyl sulfate content basis

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

description

anionic

assay

92.5-100.5% based on total alkyl sulfate content basis

mol wt

288.38 g/mol

Quality Level

greener alternative product characteristics

Catalysis
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sustainability

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aggregation number

62

technique(s)

: suitable using [cell culture | mammalian: suitable]

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

water: soluble

HLB

40

application(s)

(Western Blot)

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1 of 4

This Item
71717L4509RDD021
assay

92.5-100.5% based on total alkyl sulfate content basis

assay

≥85.0% (content of sodium alkyl sulfates)

assay

≥98.5% (GC)

assay

≥99.0%

aggregation number

62

aggregation number

-

aggregation number

62

aggregation number

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

solubility

water: soluble

solubility

water: soluble

solubility

water: soluble

solubility

water: soluble 100 mg/mL (opalescent solution)

CMC

7-10 mM (20-25°C)

CMC

-

CMC

7-10 mM (20-25°C)

CMC

-

mol wt

288.38 g/mol

mol wt

288.38 g/mol

mol wt

micellar avg mol wt 18,000

mol wt

288.38 g/mol

Analysis Note

Actual composition given on label
Predominantly (approx. 70%) C12; lauryl sulfate, sodium salt; balance consists of higher homologs.

Application

Anionic detergent
Sodium dodecyl sulfate has been used:
  • to dissolve insoluble purple formazan in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay[1]
  • to perform SDS–PAGE of yeast tubulin[2]
  • as an additive in linolenic acid solution to assess the total antioxidative activity (TAA) of the bacteria using the linolenic acid test (LA-test)[3]

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS)/lauryl sulfate, an ionic detergent has the ability to distract biological membranes. It can block RNase and deoxyribonuclease (DNase) activity. SDS is one of the main constituents of several reagents, that are used to purify nucleic acids.[4] It is also considered as a permeability enhancer in oral formulations.[5]

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is used as a surfactant to enhance catalysis.  Click here for more information.

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

338.0 °F

flash_point_c

170 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Certificates of Analysis (COA)

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Resilient Ribonucleases
RNA Methodologies (2010)
The two alpha-tubulin isotypes in budding yeast have opposing effects on microtubule dynamics in vitro
Bode CJ, et al.
EMBO Reports, 4(1), 94-99 (2003)
Safety and efficacy of self-assembling bubble carriers stabilized with sodium dodecyl sulfate for oral delivery of therapeutic proteins
Lin P Y, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 259, 168-175 (2017)
Ursolic, oleanolic and betulinic acids: antibacterial spectra and selectivity indexes.
Fontanay S, et al.
Journal of Ethnopharmacology, 120(2), 272-276 (2008)
Two antioxidative lactobacilli strains as promising probiotics
Kullisaar T, et al.
International Journal of Food Microbiology, 72(3), 215-224 (2002)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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