PHR1235

Retinyl Palmitate (Vitamin A Palmitate)

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Retinyl palmitate, Vitamin A palmitate, all−trans−Retinol palmitate
• Empirical Formula (Hill Notation): C₃₆H₆₀O₂
• CAS Number: 79-81-2
• Molecular Weight: 524.86
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329823240
• EC Number: 201-228-5
• Beilstein/REAXYS Number: 1917366
• MDL number: MFCD00019414

Properties

• Product Name: Retinyl Palmitate (Vitamin A Palmitate), Pharmaceutical Secondary Standard; Certified Reference Material
• InChI: 1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+
• InChI key: VYGQUTWHTHXGQB-FFHKNEKCSA-N
• SMILES string: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1
• grade: certified reference material; pharmaceutical secondary standard
• agency: traceable to USP 1602502
• API family: retinyl compounds
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• Quality Level: 300

Description

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Application

Retinyl palmitate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic[1] and spectrophotometric[2] techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Review: Vitamin A metabolism.

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.Retinyl palmitate belongs to a category of compounds called retinoids, which are chemically similar to vitamin A. It exhibits a beneficial effect on vision, skin and immune function, inhibits cell proliferation and prevents cancer. It is an important dietary as well as a therapeutic compound.[3]

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC1694 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H360D,H412
• pcodes: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Aquatic Chronic 3 - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 2
• flash_point_f: No data available
• flash_point_c: No data available