A4159

L-Asparagine

BioReagent, suitable for cell culture, suitable for insect cell culture

• Synonym(s): (S)-2-Aminosuccinic acid 4-amide, L-Aspartic acid 4-amide
• Linear Formula: H₂NCOCH₂CH(NH₂)CO₂H
• CAS Number: 70-47-3
• Molecular Weight: 132.12
• NACRES: NA.75
• PubChem Substance ID: 24890831
• eCl@ss: 32160406
• UNSPSC Code: 12352209
• EC Number: 200-735-9
• MDL number: MFCD00064401
• Beilstein/REAXYS Number: 1723527

Properties

• product line: BioReagent
• Quality Segment: 400
• assay: ≥98% (HPLC)
• form: powder
• technique(s): cell culture | insect: suitable, cell culture | mammalian: suitable
• color: white
• mp: 235 °C (dec.) (lit.)
• application(s): agriculture
• SMILES string: N[C@@H](CC(N)=O)C(O)=O
• InChI: 1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1
• InChI key: DCXYFEDJOCDNAF-REOHCLBHSA-N

Description

Application

L-Asparagine is used in cell culture media and is a component of MEM non-essential amino acids solution. L-Asparagine has been shown to enhance ornithine decarboxylase activity in cultured human colon adenocarcinoma Caco-2 cells and in cultured IEC-6 intestinal epithelial cells. Spore germination in Bacillus subtilis has been increased in the presence of L-asparagine.
An isoxazoline RGD mimic platelet GPIIb/IIIa antagonist has been prepared by chiral synthesis with L-asparagine as a starting material. L-Asparagine has been utilized in the synthesis of 4-azalysine building blocks for application to combinatorial chemistry.

Safety Information

• Storage Class: 11 - Combustible Solids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)