D6571
3′,4′-Dimethoxyflavone
Synonym(s):
2-(3,4-Dimethoxyphenyl)chromen-4-one, 3′,4′-DMF
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 377,00 PLN 320,45 PLN |
25 mg | Please contact Customer Service for Availability | 1.430,00 PLN |
About This Item
Empirical Formula (Hill Notation):
C17H14O4
CAS Number:
Molecular Weight:
282.29
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
320,45 PLN
List Price377,00 PLNSave 15%Please contact Customer Service for Availability
assay
≥98% (HPLC)
Quality Segment
form
powder
color
white to off-white
solubility
DMSO: ≥20 mg/mL
storage temp.
room temp
SMILES string
COc1ccc(cc1OC)C2=CC(=O)c3ccccc3O2
InChI
1S/C17H14O4/c1-19-15-8-7-11(9-17(15)20-2)16-10-13(18)12-5-3-4-6-14(12)21-16/h3-10H,1-2H3
InChI key
ZGHORMOOTZTQFL-UHFFFAOYSA-N
Application
3′,4′-Dimethoxyflavone has been used in urease inhibition assay.
Biochem/physiol Actions
3′,4′-dimethoxyflavone is a competitive antagonist of the AhR that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines. The compound blocks transformation of the cytosolic AhR complex, and formation of nuclear AhR complexes.
3′,4′-dimethoxyflavone is a competitive antagonist of the aryl hydrocarbon receptor (AhR) that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines.
3′,4′-Dimethoxyflavone is a flavone compound, which has the ability to prevent the production and accumulation of poly (ADP-ribose) (PAR) polymer. It guards against N-methyl-D-aspartate (NMDA) toxicity in cortical neurons. 3′,4′-Dimethoxyflavone is a member of the class of plant-derived polyphenolic flavonoids. It is known to have antioxidant, anti-cancer, anti-inflammatory, anti-atherogenic, hypolipidemic and neuroprotective or neurotrophic effects.
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This Item | |||
|---|---|---|---|
| description - | description AldrichCPR | description AldrichCPR | description ≥90% (LC/MS-ELSD) |
| form powder | form solid | form solid | form solid |
| assay ≥98% (HPLC) | assay - | assay - | assay ≥90% (LC/MS-ELSD) |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level - |
| storage temp. room temp | storage temp. - | storage temp. - | storage temp. −20°C |
| solubility DMSO: ≥20 mg/mL | solubility - | solubility - | solubility - |
| color white to off-white | color - | color - | color - |
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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