E0907
Anti-phospho-Epidermal Growth Factor Receptor (pTyr845) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-phospho-EGFR (pTyr845)
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
FACS, IHC, WB
Citations:
3
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human
technique(s)
flow cytometry: 5 μg/mL, immunohistochemistry: 15 μg/mL, western blot: 0.5 μg/mL
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... EGFR(1956)
Immunogen
purified, synthetic phosphopeptide corresponding to residues surrounding tyrosine 845 of human epidermal growth factor receptor.
Biochem/physiol Actions
EGFR is a transmembrane glycoprotein that binds to the EGF family. It is a pivotal regulator of cell proliferation, growth, differentiation and DNA repair after radiation-induced damage. Mutations in the gene encoding EGFR are associated with a number of malignancies including lung cancer and colorectal cancer. Phosphorylation of Tyr845 is associated with EGFR mutation and serves as a surrogate marker.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
13 - Non Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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