SAB4503499

Anti-Cyclin A antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Cyclin A1, cyclin A1
• MDL number: MFCD00243105

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 52 kDa
• species reactivity: rat, human, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P78396
• UniProt accession no.: P78396
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... CCNA1(8900)

Description

General description

Anti-Cyclin A Antibody detects endogenous levels of total Cyclin A protein.

CCNA1 (cyclin A1) is a member of the highly conserved cyclin family. There are two A-type cyclins, namely cyclin A1 and cyclin A2. Cyclin A1 is expressed at high levels in testis and expressed at low levels in most other tissues. This gene is mapped to human chromosome 13q13.

Immunogen

The antiserum was produced against synthesized peptide derived from human Cyclin A.

Immunogen Range: 221-270

Application

Anti-Cyclin A antibody has been used in western blotting.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

CCNA1 (cyclin A1) controls cell apoptosis. Cyclin A2 is required for DNA replication and proliferation in somatic cells. CCNA1 plays an important role in head and neck carcinoma and cervical and nasopharyngeal cancers.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable