1225703

Doxorubicin hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Adriamycin hydrochloride, DOX, Hydroxydaunorubicin hydrochloride
• Empirical Formula (Hill Notation): C₂₇H₂₉NO₁₁ · HCl
• CAS Number: 25316-40-9
• Molecular Weight: 579.98
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749677
• MDL number: MFCD00077757
• Beilstein/REAXYS Number: 4229251

Properties

• Product Name: Doxorubicin hydrochloride, United States Pharmacopeia (USP) Reference Standard
• SMILES string: Cl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
• InChI key: MWWSFMDVAYGXBV-RUELKSSGSA-N
• InChI: 1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
• grade: pharmaceutical primary standard
• API family: doxorubicin
• manufacturer/tradename: USP
• mp: 216 °C (dec.) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• Gene Information: human ... TOP2A(7153)

Description

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Doxorubicin hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Doxorubicin Hydrochloride Injection
• Doxorubicin Hydrochloride for Injection
• Epirubicin Hydrochloride
• Epirubicin Hydrochloride Injection

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H340,H350,H360FD
• pcodes: P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable