AR
androgen receptor
Synonimy:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Gatunek:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), fruit fly ar (44503), Zebrafish ar (100005148), chicken AR (422165), dog AR (403588), domestic cat AR (101081787), domestic cat AR (751827), Horse AR (100033980) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- fruit fly(44503) abdomen rotatum
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- dog(403588) androgen receptor
- domestic cat(101081787) androgen receptor
- domestic cat(751827) androgen receptor
- Horse(100033980) androgen receptor
- cow(280675) androgen receptor
- sheep(443042) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- domestic guinea pig(100726891) androgen receptor
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Small Molecule - Activator
Numer produktu
Opis
Gatunek
Small Molecule - Agonist
Numer produktu
Opis
Gatunek
Small Molecule - Antagonist
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Androgen Receptor antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-AR antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
dog, horse, human, pig
Zastosowanie
western blot
Anti-Androgen Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ChIP
ELISA
immunohistochemistry
western blot
ELISA
immunohistochemistry
western blot
Przeciwciało przeciwkoreceptorowi androgenowemuwytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot
western blot
Receptor anty-androgenowy, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
Numer produktu
Opis
Gatunek
Small Molecule - Inhibitor
Small Molecule - Ligand
Proteins
Numer produktu
Opis
Gatunek
Androgen receptor (650-920), human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Gatunek
human