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MAP2K5

mitogen-activated protein kinase kinase 5

Synonimy:
HsT17454, MAPKK5, MEK5, PRKMK5
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5607) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
  • Mouse(23938) mitogen-activated protein kinase kinase 5
  • Rat(29568) mitogen activated protein kinase kinase 5
  • Domestic Rabbit(100358715) mitogen-activated protein kinase kinase 5
  • domestic cat(101100725) mitogen-activated protein kinase kinase 5
  • sheep(101104069) mitogen-activated protein kinase kinase 5
  • chicken(415557) mitogen-activated protein kinase kinase 5
  • dog(609559) mitogen-activated protein kinase kinase 5
  • cow(100295732) mitogen-activated protein kinase kinase 5
  • domestic guinea pig(100732076) mitogen-activated protein kinase kinase 5
  • naked mole-rat(101711080) mitogen-activated protein kinase kinase 5
  • Horse(100052849) mitogen-activated protein kinase kinase 5
  • Zebrafish(100007679) mitogen-activated protein kinase kinase 5

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-MAP2K5 antibody produced in mouse, clone M1-E6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

western blot
Monoclonal Anti-MAP2K5, (N-terminal) antibody produced in mouse, clone 3E10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

western blot
Monoclonal Anti-MAP2K5 antibody produced in mouse, clone 1E5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

proximity ligation assay

western blot
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
PD 98,059, solid,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MAP2K5,
Gatunek
human
MISSION® esiRNA, targeting mouse Map2k5,
Gatunek
mouse