MMP14
matrix metallopeptidase 14 (membrane-inserted)
Synonimy:
MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1
Gatunek:
Human MMP14 (4323), Mouse Mmp14 (17387), Rat Mmp14 (81707), naked mole-rat Mmp14 (101723795), sheep MMP14 (443116), cow MMP14 (281915), Domestic Rabbit MMP14 (100009598), domestic guinea pig Mmp14 (100732039), dog MMP14 (403823), Horse MMP14 (100034170) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(4323) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
- Mouse(17387) matrix metallopeptidase 14 (membrane-inserted)
- Rat(81707) matrix metallopeptidase 14 (membrane-inserted)
- naked mole-rat(101723795) matrix metallopeptidase 14 (membrane-inserted)
- sheep(443116) matrix metallopeptidase 14 (membrane-inserted)
- cow(281915) matrix metallopeptidase 14 (membrane-inserted)
- Domestic Rabbit(100009598) matrix metallopeptidase 14 (membrane-inserted)
- domestic guinea pig(100732039) matrix metallopeptidase 14 (membrane-inserted)
- dog(403823) matrix metallopeptidase 14 (membrane-inserted)
- Horse(100034170) matrix metallopeptidase 14 (membrane-inserted)
- domestic cat(101089776) matrix metallopeptidase 14 (membrane-inserted)
- chicken(426253) matrix metallopeptidase 14 (membrane-inserted)
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MMP-14 Antibody, catalytic domain, clone LEM-2/63.1, clone LEM-2/63.1, Chemicon®, from mouse,
Reaktywność gatunkowa
mouse
Zastosowanie
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-MT1-MMP Antibody, hinge region, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Przeciwciało anty-MMP-14, serum, Chemicon®,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunocytochemistry
immunoprecipitation (IP)
western blot
Przeciwciało anty-MMP-14, domena katalityczna, klon 114-6G6, clone 114-6G6, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MMP-14 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Numer produktu
Opis
Gatunek
MMP-14, ludzka, prodomena, domena katalityczna i domena hemopeksyny, rekombinowana w E. coli, ,
Gatunek
human