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MYC

v-myc avian myelocytomatosis viral oncogene homolog

Synonimy:
MRTL, MYCC, bHLHe39, c-Myc
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17869) myelocytomatosis oncogene
  • Rat(24577) myelocytomatosis oncogene
  • chicken(420332) v-myc myelocytomatosis viral oncogene homolog
  • dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
  • cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
  • sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)
  • Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Ludzki c-Myc ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-MYC antibody produced in mouse, clone 1G7, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-MYC antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-MYC, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Zastosowanie
western blot
Anti-MyC antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
human, pig, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
Monoclonal Anti-MYC-FITC , (C-terminal) antibody produced in mouse, clone 9E10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
fusion proteins in all species, human
Zastosowanie
flow cytometry

Proteins

Numer produktu
Opis
Gatunek
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MYC,
Gatunek
human
MISSION® esiRNA, targeting mouse Myc,
Gatunek
mouse