MYC
v-myc avian myelocytomatosis viral oncogene homolog
Synonimy:
MRTL, MYCC, bHLHe39, c-Myc
Gatunek:
Human MYC (4609), Mouse Myc (17869), Rat Myc (24577), chicken MYC (420332), dog MYC (403924), domestic cat MYC (100379628), cow MYC (511077), sheep MYC (443447), Domestic Rabbit MYC (100327265), domestic guinea pig Myc (100724557)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
- Mouse(17869) myelocytomatosis oncogene
- Rat(24577) myelocytomatosis oncogene
- chicken(420332) v-myc myelocytomatosis viral oncogene homolog
- dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
- domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
- cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
- sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)
- Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
- domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)
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ELISA
Numer produktu
Opis
Gatunek
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-c-Myc−FITC antibody produced in mouse, clone 9E10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
Anti-c-Myc−Peroxidase antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-c-Myc antibody produced in rabbit, ~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
microarray
western blot
immunofluorescence
immunoprecipitation (IP)
microarray
western blot
Anti-c-Myc antibody, Mouse monoclonal, clone 9E10, purified from hybridoma cell culture,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Przeciwciało anty-Myc Tag, klon 4A6, clone 4A6, Upstate®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
ChIP
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
Proteins
Numer produktu
Opis
Gatunek
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human