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Merck

OSCAR

osteoclast associated, immunoglobulin-like receptor

Synonimy:
PIGR3, PIgR-3
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(126014) Summary: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(232790) osteoclast associated receptor
  • Rat(292537) osteoclast associated, immunoglobulin-like receptor
  • cow(100336423) osteoclast associated, immunoglobulin-like receptor
  • dog(484313) osteoclast associated, immunoglobulin-like receptor

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-OSCAR, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence