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PPARG

peroxisome proliferator-activated receptor gamma

Synonimy:
CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5468) Summary: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(19016) peroxisome proliferator activated receptor gamma
  • Rat(25664) peroxisome proliferator-activated receptor gamma
  • Zebrafish(557037) peroxisome proliferator activated receptor gamma
  • chicken(373928) peroxisome proliferator-activated receptor gamma
  • cow(281993) peroxisome proliferator-activated receptor gamma
  • naked mole-rat(101711078) peroxisome proliferator-activated receptor gamma
  • Goat(100861309) peroxisome proliferator-activated receptor gamma
  • domestic cat(100049014) peroxisome proliferator-activated receptor gamma
  • domestic cat(101095161) peroxisome proliferator-activated receptor gamma
  • domestic guinea pig(100729138) peroxisome proliferator-activated receptor gamma
  • sheep(443513) peroxisome proliferator-activated receptor gamma
  • dog(403606) peroxisome proliferator-activated receptor gamma

Custom & Knockdown Gene Products

Small Molecule - Activator

Numer produktu
Opis
Gatunek
Ciglitizone, ≥98% (HPLC),
Gatunek
mouse, human
2-(p-Chlorophenoxy)-2-methylpropionic acid, 97%,
Gatunek
mouse, human
WY-14643, ,
Gatunek
rat, human, mouse
Bezafibrate, ≥98%, solid,
Gatunek
mouse, human

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Rosiglitazone, ,
Gatunek
human
Pioglitazone for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Pioglitazone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Pioglitazone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
GW1929 hydrate, >98% (HPLC), solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
GW9662, >98% (HPLC),
Gatunek
human
Troglitazone, ≥98% (HPLC),
Gatunek
human
Ciglitizone, ≥98% (HPLC),
Gatunek
mouse, human
GW0742, ≥98% (HPLC),
Gatunek
human
CDDO Methyl Ester, ≥98% (HPLC),
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PPAR-γ antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-PPARG (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
Anti-phospho-PPAR-γ (pSer112) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Przeciwciało anty-PPARgamma wytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Przeciwciało anty-fosfo-PPARgamma (Ser112), klon AW504 króliczy monoklonalny, ,
Reaktywność gatunkowa
Zastosowanie
western blot

Proteins

Numer produktu
Opis
Gatunek
PPAR, γ human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Gatunek
human
PPAR γ, ligand binding domain (204-477), GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PPARG,
Gatunek
human
MISSION® esiRNA, targeting mouse Pparg,
Gatunek
mouse