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Merck

PTGER4

prostaglandin E receptor 4 (subtype EP4)

Synonimy:
EP4, EP4R
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5734) Summary: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
  • Mouse(19219) prostaglandin E receptor 4 (subtype EP4)
  • Rat(84023) prostaglandin E receptor 4 (subtype EP4)
  • sheep(101104343) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(100169968) prostaglandin E receptor 4 (subtype EP4)
  • naked mole-rat(101723705) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(101094734) prostaglandin E receptor 4 (subtype EP4)
  • domestic guinea pig(100192398) prostaglandin E receptor 4 (subtype EP4)
  • Domestic Rabbit(100009081) prostaglandin E receptor 4 (subtype EP4)
  • dog(403589) prostaglandin E receptor 4 (subtype EP4)
  • chicken(427183) prostaglandin E receptor 4 (subtype EP4)
  • sheep(443222) prostaglandin E receptor 4 (subtype EP4)
  • cow(282331) prostaglandin E receptor 4 (subtype EP4)

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Dinoprostone, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Dinoprostone, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Gatunek
human, mouse
Prostaglandin E1, powder, γ-irradiated, BioXtra, suitable for cell culture,
Gatunek
human, mouse
Prostaglandin E1, ≥98% (HPLC), synthetic,
Gatunek
human, mouse

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Gatunek
human, mouse
Prostaglandin E1, powder, γ-irradiated, BioXtra, suitable for cell culture,
Gatunek
human, mouse
Prostaglandin E1, ≥98% (HPLC), synthetic,
Gatunek
human, mouse
Prostaglandin E2, γ-irradiated, powder, BioXtra, suitable for cell culture,
Gatunek
human, mouse
Prostaglandin E2, synthetic, powder, BioReagent, suitable for cell culture,
Gatunek
human, mouse

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-EP4 Prostaglandin Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
canine, human
Zastosowanie
ELISA
western blot
Anti-PE2R4 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

western blot

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
Prostaglandin E2, ≥93% (HPLC), synthetic,
Gatunek
mouse, human
Indomethacin, 98.0-102.0%, meets EP testing specifications,
Gatunek
human, mouse, rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PTGER4,
Gatunek
human
MISSION® esiRNA, targeting mouse Ptger4,
Gatunek
mouse