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Merck

ROCK2

Rho-associated, coiled-coil containing protein kinase 2

Synonimy:
ROCK-II
Gatunek:
Human ROCK2 (9475), Mouse Rock2 (19878), Rat Rock2 (25537), domestic cat ROCK2 (101094501), sheep ROCK2 (101103800), chicken ROCK2 (374182), naked mole-rat Rock2 (101724195), cow ROCK2 (282041), sheep ROCK2 (100294663), domestic guinea pig Rock2 (100713798)
Identyfikator UniProtKB:
O75116, Q53QZ0, Q53SJ7, Q9UQN5
Identyfikator genu:
  • Human(9475) Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]
  • Mouse(19878) Rho-associated coiled-coil containing protein kinase 2
  • Rat(25537) Rho-associated coiled-coil containing protein kinase 2
  • domestic cat(101094501) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(101103800) Rho-associated, coiled-coil containing protein kinase 2
  • chicken(374182) Rho-associated, coiled-coil containing protein kinase 2
  • naked mole-rat(101724195) Rho-associated, coiled-coil containing protein kinase 2
  • cow(282041) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(100294663) Rho-associated, coiled-coil containing protein kinase 2
  • domestic guinea pig(100713798) Rho-associated, coiled-coil containing protein kinase 2
  • dog(482970) Rho-associated, coiled-coil containing protein kinase 2

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
WH0009475M1
Monoclonal Anti-ROCK2 antibody produced in mouse, clone 2A4, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
western blot
HPA007459
Anti-ROCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
HPA044109
Anti-ROCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
SAB4301564
Anty-fosfoROCK2(pTyr722), affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
SAB1404727
Monoclonal Anti-ROCK2, (C-terminal) antibody produced in mouse, clone 1E12, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Y0503
Y-27632 dihydrochloride, ≥98% (HPLC),
Gatunek
human
A5665
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
Gatunek
human, rat, mouse
A2786
Adenine, BioReagent, suitable for cell culture,
Gatunek
human, rat, mouse
A8626
Adenine, ≥99%,
Gatunek
human, rat, mouse

Proteins

Numer produktu
Opis
Gatunek
SRP5214
ROCK2 (5-554), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU030131
MISSION® esiRNA, targeting human ROCK2,
Gatunek
human