02252

(−)-Epinephrine

tested according to USP

• Synonim(y): (−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine
• Wzór liniowy: (HO)₂C₆H₃CH(OH)CH₂NHCH₃
• Numer CAS: 51-43-4
• Masa cząsteczkowa: 183.20
• EC Number: 200-098-7
• UNSPSC Code: 12352200
• PubChem Substance ID: 24845246
• Beilstein/REAXYS Number: 2368277
• MDL number: MFCD00002204

Właściwości

• agency: tested according to USP
• mp: 215 °C (dec.) (lit.)
• solubility: H₂O: very slightly soluble, NaOH: very soluble, acetone: insoluble, alcohol: very slightly soluble, chloroform: insoluble, diethyl ether: insoluble, oil: insoluble, potassium hydroxide solution: very soluble
• application(s): pharmaceutical (small molecule)
• storage temp.: 2-8°C
• SMILES string: CNC[C@H](O)c1ccc(O)c(O)c1
• InChI: 1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1
• InChI key: UCTWMZQNUQWSLP-VIFPVBQESA-N
• Gene Information: rat ... Adra1a(29412), Adra2a(25083), Adrb1(24925), Adrb2(24176), Drd1a(24316), Drd2(24318)

Opis

Application

(-)-Epinephrine was used in fertilization medium for rinsing Cumulus-oocyte complexes (COC) during in vitro maturation.

Biochem/physiol Actions

(-)-Epinephrine enhances the IL-6 secretion and bioactivity from isolated perfused rat liver (IPRL).

Adrenoceptor agonist.

Preparation Note

(-)-Epinephrine readily dissolves in aqueous solutions of mineral acids, KOH and NaOH. It is very slightly soluble in water and alcohol but is insoluble in chloroform, ether, acetone, oils as well as in aqueous solutions of ammonia and the alkali carbonates.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H301 + H331,H310
• Ostrzeżenia: P261 - P262 - P280 - P301 + P310 - P302 + P352 + P310 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Klasa składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges