C9523

Sodium cholesteryl sulfate

• Synonim(y): 5-Cholesten-3β-ol sulfate sodium salt, Cholesterol 3-sulfate sodium salt, Cholesteryl sodium sulfate, Cholesteryl sulfate sodium salt
• Wzór empiryczny (zapis Hilla): C₂₇H₄₅NaO₄S
• Numer CAS: 2864-50-8
• Masa cząsteczkowa: 488.70
• NACRES: NA.77
• PubChem Substance ID: 24893166
• eCl@ss: 39023139
• UNSPSC Code: 41141804
• MDL number: MFCD00079091
• Beilstein/REAXYS Number: 3899884

Właściwości

• biological source: synthetic
• Quality Segment: 200
• description: anionic
• assay: ≥98% (TLC)
• form: powder
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: [H][C@@]([C@H](C)CCCC(C)C)([C@@]1(C)CC[C@@]23[H])CC[C@]1([C@](CC=C4C[C@H](CC[C@]34C)OS([O-])(=O)=O)2[H])[H].[Na+]
• InChI: 1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1
• InChI key: LMPVQXVJTZWENW-KPNWGBFJSA-M

Opis

Application

Sodium cholesteryl sulfate was used as the source of cholesterol in the preparation of Edgar′s growth medium used for embryology experiments. It was used as a standard for the separation of human stratum corneum lipids by thin layer chromatography.

Biochem/physiol Actions

Cholesteryl sulfate is a natural constituent of human spermatozoa and has major role in the maturation of sperms. It could also be involved in the capacitation of sperms and enables ovum penetration. Low concentrations of cholesteryl sulfate inhibits acrosin, the proteinase present in sperm acrosome that facilitates ovum penetration.

Preparation Note

Sodium cholesteryl sulfate yields clear, colorless solution in chloroform-methanol (1:1) mixture at 10 mg/ml.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)