SML4446

LDM

≥98% (HPLC)

• Synonim(y): DCOH-FR-Ocl, LDM lipid droplet probe, O-[4-[2-[3-(Dicyanomethylene)-5,5-dimethyl-1-cyclohexen-1-yl]ethenyl]phenyl] N,N-dimethylcarbamothioate
• Wzór empiryczny (zapis Hilla): C₂₂H₂₃N₃OS
• Numer CAS: 2408641-99-4
• Masa cząsteczkowa: 377.50
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Opis

Biochem/physiol Actions

LDM is a cell penetrant lipid droplets fluorescent probe that selectively visualize the neutral lipid core of lipid droplets (LDs). LDM is activated by the HClO/ClO- present in the lipid droplets microenvironment to generate LDM-OH which selectively visualizes lipid droplet (LD) membrane by binding to LD associated proteins through electrostatic interactions. The HClO/ClO- activation transforms the green fluorescent pro-probe LDM (emission at 522 nm) to a red fluorescent LDM-OH (far-red emission at 637 nm). Also LDM (DCOH-FR-OCl) can be effectively utilized in the real-time imaging of endogenous and exogenous OCl- in living cells.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302,H315
• Ostrzeżenia: P264 - P280 - P301 + P312 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Acute Tox. 4 Oral - Skin Irrit. 2
• Klasa składowania: 11 - Combustible Solids
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable