Hydrolysis of single linkage in long DNA using oligonucleotide-multiphosphonate conjugates and Ce IV/EDTA.

Hydrolysis of single linkage in long DNA using oligonucleotide-multiphosphonate conjugates and Ce IV/EDTA.

Nucleic acids symposium series (2004) (2008-09-09)

Yuta Suzuki, Tuomas Lönnberg, Makoto Komiyama

ABSTRAKT

Only one phosphodiester linkage in long DNA was hydrolyzed simply by using two components: oligonucleotide-multiphosphonate conjugates ("gapmers") and Ce(IV)/EDTA (Fig. 1).

MATERIAŁY

Numer produktu

Marka

Opis produktu

72568

Sigma-Aldrich

Nitrilotri(methylphosphonic acid), ≥95% (T)