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Merck

An efficient and economic asymmetric synthesis of (+)-nootkatone, tetrahydronootkatone, and derivatives.

Organic letters (2009-07-28)
Anne M Sauer, William E Crowe, Gregg Henderson, Roger A Laine
ABSTRAKT

A facile route to enantiomerically pure (+)-nootkatone and derivatives has been established through conjunctive stereoselective Grignard/anionic oxy-Cope (AOC) reactions.

MATERIAŁY
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Sigma-Aldrich
(+)-Nootkatone, ≥99.0% (GC)