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Merck

Acetazolamide-induced cilio-choroidal effusion after cataract surgery: unusual posterior involvement.

Drug design, development and therapy (2013-02-05)
Romualdo Malagola, Loredana Arrico, Rossella Giannotti, Luigi Pattavina
ABSTRAKT

Idiosyncratic reactions to a large number of drugs have been reported to cause choroidal detachment and secondary angle-closure glaucoma (ACG). We report a case of bilateral acute ACG and peculiar choroidal effusion following administration of oral acetazolamide immediately after cataract surgery. Few cases of acute secondary ACG with choroidal effusion and anterior shift of the lens-iris diaphragm have been associated with acetazolamide compared with other sulfonamides. As far as we are aware, posterior involvement with retinal folds and papillary edema due to acetazolamide has not been described before.

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Acetazolamide, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
Acetazolamide, ≥99%, powder