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Merck

[Studies on the lignans from Patrinia scabra].

Yao xue xue bao = Acta pharmaceutica Sinica (2003-10-01)
Ting-zhao Li, Wei-dong Zhang, Zheng-bing Gu, Wen-yong Liu, Jing Zhou, Wan-sheng Chen
ABSTRAKT

To study the lignans from Patrinia scabra Bunge. The constituents were separated and purified by column chromatography with silical gel, RP-silical gel and Sephadex LH-20. Their structures were identified on the basis of spectral data (IR, MS, 1HNMR, 13CNMR, HMQC and HMBC). A new lignan was obtained and its structure was elucidated as 4-[1-ethoxyl-1-(4-hydroxy-3-methoxy)benzyl]methyl- 2-(4-hydroxy-3-methoxy)benzyl-3-hydroxymethyl-tetrahydro-furan (2), along with three known lignans, lariciresinol (1), isolariciresinol (3) and nortracheloside (4).