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Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia.

Scientific reports (2016-10-06)
Joachim Ruther, Åsa K Hagström, Birgit Brandstetter, John Hofferberth, Astrid Bruckmann, Florian Semmelmann, Michaela Fink, Helena Lowack, Sabine Laberer, Oliver Niehuis, Rainer Deutzmann, Christer Löfstedt, Reinhard Sterner
ABSTRAKT

Males of all species of the parasitic wasp genus Nasonia use (4R,5S)-5-hydroxy-4-decanolide (RS) as component of their sex pheromone while only N. vitripennis (Nv), employs additionally (4R,5R)-5-hydroxy-4-decanolide (RR). Three genes coding for the NAD