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Merck

Piperine regulates UCP1 through the AMPK pathway by generating intracellular lactate production in muscle cells.

Scientific reports (2017-01-25)
Nami Kim, Miso Nam, Mi Sun Kang, Jung Ok Lee, Yong Woo Lee, Geum-Sook Hwang, Hyeon Soo Kim
ABSTRAKT

This study characterizes the human metabolic response to piperine, a curcumin extract, and the details of its underlying molecular mechanism. Using

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Sigma-Aldrich
Guanosine 5′-diphosphate sodium salt, Type I, ≥96% (HPLC)
Sigma-Aldrich
Dorsomorphin, ≥98% (HPLC)