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Diethylenetriaminepentaacetic acid

≥99% (titration)

DETAPAC, (Carboxymethylimino)bis(ethylenenitrilo)tetraacetic acid, Pentetic acid, Penta(carboxymethyl)diethylenetriamine, DTPA, N,N-Bis(2-[bis(carboxymethyl)amino]ethyl)glycine
Linear Formula:
CAS Number:
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EC Number:
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Quality Level

biological source

synthetic (organic)


≥99% (titration)




219-220 °C (lit.)


1 M HCl: 50 mg/mL, clear, colorless

storage temp.

room temp

SMILES string




InChI key


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General description

Diethylenetriaminepentaacetic acid is a diethylenetriaminepentaacetic anhydride, which is a bifunctional chelating agent. It is used for the treatment of poisoning.


Diethylenetriaminepentaacetic acid has been used:
  • for cofilin activity assay
  • to determine the specificity of superoxide in the transverse aortic constriction (TAC) hearts
  • for Europium bead-based detection assays
  • to detect reduced (S- active) or irreversibly oxidized (SO3H inactive) tyrosine-protein phosphatase non-receptor type 6 (SHP-1) in thymocytes


5, 10, 50, 100 g in glass bottle

Preparation Note



Exclamation markHealth hazard

Signal Word


Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 2 - STOT RE 2 Inhalation

Target Organs

Respiratory Tract

Storage Class Code

13 - Non Combustible Solids



Flash Point(F)

392.0 °F - closed cup

Flash Point(C)

200 °C - closed cup

Certificate of Analysis

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Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. How can I get Product D6518, Diethylenetriaminepentaacetic acid, to dissolve?

    As is the case with other chelating agents such as EDTA and EGTA, the solubility of DTPA is a function of pH.  Therefore, this compound can be solubilized with either the addition of acid such as a hydrochloric acid solution or (more likely) base such as a sodium hydroxide solution .

  6. What are the pKa values for Product D6518, Diethylenetriaminepentaacetic acid?

    The pKa values for the carboxyl groups as reported in the reference book "Data for Biochemical Research, 3rd ed., page 402, Oxford University Press, New York (1986)." are 1.8, 2.6, 4.4, 8.8, and 10.4.

  7. What cations can be chelated with Product D6518, Diethylenetriaminepentaacetic acid (DTPA)?

    DTPA forms stable complexes with most divalent and trivalent cations.  Some examples are Fe3+, Cu2+, Ni2+, Pb2+, Zn2+, Fe2+, Mn2+, Ca2+,  Mg2+, and Ba2+.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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