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Merck

90568

Fenofibric acid

analytical standard

Synonym(s):

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid, Fenofibric acid

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10 MG

986,00 kr

986,00 kr

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About This Item

Empirical Formula (Hill Notation):
C17H15ClO4
CAS Number:
42017-89-0
Molecular Weight:
318.75
UNSPSC Code:
77101502
NACRES:
NA.24
PubChem Substance ID:
329769927
EC Number:
255-626-9
Beilstein/REAXYS Number:
2058973
MDL number:
MFCD00792461

Key Documents

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Product Name

Fenofibric acid, analytical standard

SMILES string

O=C(C1=CC=C(OC(C)(C)C(O)=O)C=C1)C2=CC=C(Cl)C=C2

InChI

1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)

InChI key

MQOBSOSZFYZQOK-UHFFFAOYSA-N

grade

analytical standard

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤1.0% water

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

Gene Information

human ... PPARA(5465)

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1 of 4

This Item
41326PHR124690323
Fenofibric acid analytical standard

Supelco

90568

Fenofibric acid

Clofibrate analytical standard

Supelco

41326

Clofibrate

Fenofibrate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1246

Fenofibrate

Clofibric acid analytical standard

Supelco

90323

Clofibric acid

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

Quality Level

100

Quality Level

100

Quality Level

300

Quality Level

100

grade

analytical standard

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

analytical standard

assay

≥98.0% (HPLC)

assay

≥99.0% (GC)

assay

-

assay

≥99.0% (GC)

Application

Fenofibric acid may be used as a reference standard in the determination of fenofibric acid in samples of human plasma using high performance liquid chromatography (HPLC)[1] and liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).[2]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN3017
BCCH7546
BCCG5448
BCCC0735
BCBZ6721

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Determination of bezafibrate, ciprofibrate and fenofibric acid in human plasma by high-performance liquid chromatography.
Masnatta D L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 687(2), 437-442 (1996)
Simultaneous determination of rosuvastatin and fenofibric acid in human plasma by LC?MS/MS with electrospray ionization: assay development, validation and application to a clinical study.
Trivedi K R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 39(3-4), 661-669 (2005)
Martial Caillaud et al.
Cancers, 13(1) (2021-01-02)
Paclitaxel-induced peripheral neuropathy (PIPN) is a major adverse effect of this chemotherapeutic agent that is used in the treatment of a number of solid malignancies. PIPN leads notably to burning pain, cold and mechanical allodynia. PIPN is thought to be
Roger K Verbeeck et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 18(1), 61-67 (2015-04-17)
The therapeutic equivalence of multiple registered fenofibrate formulations, several of which are suprabioavailable and therefore marketed at lower dosage strengths than their reference products, is based on the results of bioequivalence studies. Most of these formulations show a higher bioavailability
Yunxia Lu et al.
Biochemical and biophysical research communications, 458(1), 1-7 (2015-01-17)
Fenofibrate (FF) is widely used to lower blood lipids in clinical practice, but whether its protective effect on endothelium-dependent vasodilatation (EDV) in thoracic aorta is related with endoplasmic reticulum (ER) stress remains unknown. In this study, female Sprauge Dawley rats
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