Skip to Content
Merck

SML0824

Lubeluzole dihydrochloride

≥98% (HPLC)

Synonym(s):

(aS)-4-(2-Benzothiazolylmethylamino)-a-[(3,4-difluorophenoxy)methyl]-1-piperidineethanol dihydrochloride, R 87926

Slide 1 of 1
Sign In to View Organizational & Contract Pricing.

Select a Size

5 MG

1 420,00 kr

25 MG

3 750,00 kr

1 420,00 kr

Please contact Customer Service for Availability

About This Item

Empirical Formula (Hill Notation):
C22H25F2N3O2S · 2HCl
CAS Number:
144665-07-6
Molecular Weight:
506.44
UNSPSC Code:
12352200
NACRES:
NA.77

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Lubeluzole dihydrochloride, ≥98% (HPLC)

Quality Level

100

SMILES string

Fc1c(ccc(c1)OC[C@@H](O)CN2CCC(CC2)N(C)c3[s]c4c(n3)cccc4)F

InChI

1S/C22H25F2N3O2S/c1-26(22-25-20-4-2-3-5-21(20)30-22)15-8-10-27(11-9-15)13-16(28)14-29-17-6-7-18(23)19(24)12-17/h2-7,12,15-16,28H,8-11,13-14H2,1H3/t16-/m0/s1

InChI key

OZFSWVOEXHGDES-INIZCTEOSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
SML2223S7389SML2921
Lubeluzole dihydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML0824

Lubeluzole dihydrochloride

WAY-267464 dihydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML2223

WAY-267464 dihydrochloride

SB-269970 hydrochloride powder, ≥98% (HPLC)

Sigma-Aldrich

S7389

SB-269970 hydrochloride

LYN-1604 hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML2921

LYN-1604 hydrochloride

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: 2 mg/mL, clear (warmed)

solubility

H2O: 2 mg/mL, clear

solubility

H2O: 10 mg/mL, clear (warmed to 60 °C)

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

-

color

white to beige

Biochem/physiol Actions

Lubeluzole is an NMDA antagonist.
Lubeluzole is an NMDA antagonist. Lubeluzole blocks glutamate release, as well as sodium and calcium gated ion channels. Lubeluzole displays neuroprotective properties in ischemia models.

Features and Benefits

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H413

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000292203
0000292203
0000191893
0000191893
0000084771

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jean-François Desaphy et al.
Experimental neurology, 255, 96-102 (2014-03-13)
Although the sodium channel blocker mexiletine is considered the first-line drug in myotonia, some patients experiment adverse effects, while others do not gain any benefit. Other antimyotonic drugs are thus needed to offer mexiletine alternatives. In the present study, we

Articles

Glutamate Receptors (Ion Channel Family)

We offers many products related to ion channel family glutamate receptors for your research needs.

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service