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Merck

PHR1433

Ascorbyl Glucoside

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Ascorbyl Glucoside

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About This Item

Empirical Formula (Hill Notation):
C12H18O11
CAS Number:
Molecular Weight:
338.26
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:

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Product Name

Ascorbyl Glucoside, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C12H18O11/c13-1-3(15)9-8(19)10(11(20)22-9)23-12-7(18)6(17)5(16)4(2-14)21-12/h3-7,9,12-19H,1-2H2/t3-,4+,5+,6-,7+,9+,12+/m0/s1

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(C1=O)O[C@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO

InChI key

MLSJBGYKDYSOAE-DCWMUDTNSA-N

grade

certified reference material
pharmaceutical secondary standard

API family

ascorbyl glucoside

form

solid

CofA

current certificate can be downloaded

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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This Item
PHR1455PHR1008PHR1709
application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

food and beverages

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

form

solid

form

-

form

solid

form

-

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

2-8°C

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ascorbyl Glucoside is used to protect skin from exposure to UV rays.[1]

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA2741 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Basem Kanawati et al.
Rapid communications in mass spectrometry : RCM, 25(6), 806-814 (2011-02-22)
L-Ascorbic acid and two distinct anomers, namely the α-D-glucopyranosyl and β-D-glucopyranosyl-(1→2)-L-ascorbic acid (stereoisomers), were studied within the scope of collision-induced dissociation (CID) experiments, performed by linear ion acceleration and collision with argon atoms inside a hexapole quadrupole hexapole ion beam
Yuko Kinashi et al.
Mutation research, 695(1-2), 69-74 (2009-12-17)
Evidence from in vivo studies suggests there are enhanced radiation effects in abscopal regions after local head gamma ray irradiation. Splenocyte apoptosis and T lymphocyte micronuclei were induced at higher rates than what would be estimated given the dose at
Mutsuko Taniguchi et al.
European journal of pharmacology, 674(2-3), 126-131 (2011-11-29)
A stable ascorbic acid derivative, 2-O-α-glucopyranosyl-l-ascorbic acid (AA-2G), was evaluated and compared with ascorbic acid for its protective effect against cellular damage and senescence induced by hydrogen peroxide (H(2)O(2)). Pretreatment with AA-2G for 72 h promoted the proliferation of normal
Chien-Yu Hsiao et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 38(8), 1284-1293 (2012-06-08)
Topical treatment with vitamin C has been used to treat photoaged skin and as a skin whitener, but no standard procedure exists for percutaneous delivery. To compare skin histology and the permeation of ascorbic acid 2-glucoside (AA2G) after fractional and
Akihiro Tai et al.
Carbohydrate research, 345(12), 1658-1662 (2010-06-23)
2-O-alpha-D-Glucopyranosyl-L-ascorbic acid (AA-2G) laurate was synthesized from AA-2G and vinyl laurate with a protease from Bacillus subtilis in N,N-dimethylformamide (DMF) with low water content. Addition of water to DMF dramatically enhanced monoacyl AA-2G synthesis. Maximum synthetic activity was observed when

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