CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Synonyms:
CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1
āļŠāļēāļĒāļāļąāļāļāļļāđ:
Human CDKN1A (1026), Mouse Cdkn1a (12575), Rat Cdkn1a (114851), Zebrafish cdkn1a (100151416), domestic guinea pig Cdkn1a (100720449), cow CDKN1A (513497), sheep CDKN1A (100302083), dog CDKN1A (474890), domestic cat CDKN1A (493943), naked mole-rat Cdkn1a (101710552)
UniProtKB ID:
āļĢāļŦāļąāļŠāļĒāļĩāļ:
- Human(1026) Summary: This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Nov 2010]
- Mouse(12575) cyclin-dependent kinase inhibitor 1A (P21)
- Rat(114851) cyclin-dependent kinase inhibitor 1A
- Zebrafish(100151416) cyclin-dependent kinase inhibitor 1A
- domestic guinea pig(100720449) cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- cow(513497) cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- sheep(100302083) cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- dog(474890) cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- domestic cat(493943) cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- naked mole-rat(101710552) cyclin-dependent kinase inhibitor 1A (p21, Cip1)
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Antibodies
Product Number
āļāļģāļāļāļīāļāļēāļĒ
āļāļ§āļēāļĄāļŠāļēāļĄāļēāļĢāļāđāļāļāļēāļĢāļāļāļāļŠāļāļāļāļāļāļāļŠāļēāļĒāļāļąāļāļāļļāđ
āļāļēāļĢāđāļāđāļāļēāļ
Anti-p21 Antibody, clone 5G7, ZooMAbÂŪ Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
āļāļ§āļēāļĄāļŠāļēāļĄāļēāļĢāļāđāļāļāļēāļĢāļāļāļāļŠāļāļāļāļāļāļāļŠāļēāļĒāļāļąāļāļāļļāđ
human, mouse
āļāļēāļĢāđāļāđāļāļēāļ
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-p21/WAF1/Cip1 Antibody, clone CP74, clone CP74, UpstateÂŪ, from mouse,
āļāļ§āļēāļĄāļŠāļēāļĄāļēāļĢāļāđāļāļāļēāļĢāļāļāļāļŠāļāļāļāļāļāļāļŠāļēāļĒāļāļąāļāļāļļāđ
human
āļāļēāļĢāđāļāđāļāļēāļ
immunohistochemistry
western blot
western blot
Anti-p21/WAF1/Cip1 Antibody, UpstateÂŪ, from mouse,
āļāļ§āļēāļĄāļŠāļēāļĄāļēāļĢāļāđāļāļāļēāļĢāļāļāļāļŠāļāļāļāļāļāļāļŠāļēāļĒāļāļąāļāļāļļāđ
human, mouse
āļāļēāļĢāđāļāđāļāļēāļ
immunoprecipitation (IP)
western blot
western blot
Anti-p21WAF1 Antibody, clone EA10, clone EA10, from mouse,
āļāļ§āļēāļĄāļŠāļēāļĄāļēāļĢāļāđāļāļāļēāļĢāļāļāļāļŠāļāļāļāļāļāļāļŠāļēāļĒāļāļąāļāļāļļāđ
human
āļāļēāļĢāđāļāđāļāļēāļ
flow cytometry
western blot
western blot
Anti-p21WAF1 (Ab-1) Mouse mAb (EA10), liquid, clone EA10, CalbiochemÂŪ,
āļāļ§āļēāļĄāļŠāļēāļĄāļēāļĢāļāđāļāļāļēāļĢāļāļāļāļŠāļāļāļāļāļāļāļŠāļēāļĒāļāļąāļāļāļļāđ
human
āļāļēāļĢāđāļāđāļāļēāļ
Small Molecule - Inhibitor
Proteins
Product Number
āļāļģāļāļāļīāļāļēāļĒ
āļŠāļēāļĒāļāļąāļāļāļļāđ
p21CIP1, GST tagged human, recombinant, expressed in E. coli, âĨ70% (SDS-PAGE), buffered aqueous glycerol solution,
āļŠāļēāļĒāļāļąāļāļāļļāđ
human
esiRNA
Product Number
āļāļģāļāļāļīāļāļēāļĒ
āļŠāļēāļĒāļāļąāļāļāļļāđ