MilliporeSigma

HGF

hepatocyte growth factor (hepapoietin A; scatter factor)

Synonyms:
DFNB39, F-TCF, HGFB, HPTA, SF
Species:
UniProtKB ID:
Gene ID:
  • Human(3082) Summary: Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(15234) hepatocyte growth factor
  • Rat(24446) hepatocyte growth factor
  • cow(282879) hepatocyte growth factor (hepapoietin A; scatter factor)
  • sheep(443075) hepatocyte growth factor (hepapoietin A; scatter factor)
  • Domestic Rabbit(100316908) hepatocyte growth factor (hepapoietin A; scatter factor)
  • domestic guinea pig(100730730) hepatocyte growth factor (hepapoietin A; scatter factor)
  • naked mole-rat(101707056) hepatocyte growth factor (hepapoietin A; scatter factor)
  • chicken(395941) hepatocyte growth factor (hepapoietin A; scatter factor)
  • dog(403441) hepatocyte growth factor (hepapoietin A; scatter factor)
  • domestic cat(493705) hepatocyte growth factor (hepapoietin A; scatter factor)

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ELISA

Product Number
Description
Species
Rat HGF ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
rat
Human HGF ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Human HGF ELISA Kit, for cell and tissue lysates,
Species
human
Mouse HGF ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Mouse HGF ELISA Kit, for cell and tissue lysates,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Hepatocyte Growth Factor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Hepatocyte Growth Factor antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
neutralization
western blot
Monoclonal Anti-Hepatocyte Growth Factor antibody produced in mouse, clone 24612.111, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
ELISA
neutralization

western blot
Anti-HGF antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
proximity ligation assay
western blot
Anti-HGF antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
western blot

Proteins

Product Number
Description
Species
Hepatocyte Growth Factor human, HGF, recombinant, expressed in Baculovirus infected High-5 cells, suitable for cell culture,
Species
human
Hepatocyte Growth Factor human, HGF, recombinant, expressed in NSO cells, suitable for cell culture,
Species
human
Hepatocyte Growth Factor human, HGF, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Species
human
HGF mouse, recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE), ≥95% (HPLC),
Species
mouse
HGF human, recombinant, expressed in CHO cells, ≥97% (SDS-PAGE), ≥97% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Hgf,
Species
mouse
MISSION® esiRNA, targeting human HGF,
Species
human