MilliporeSigma

ACE

angiotensin I converting enzyme

Synonyms:
ACE1, CD143, DCP, DCP1, ICH, MVCD3
Species:
UniProtKB ID:
Gene ID:
  • Human(1636) Summary: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
  • Mouse(11421) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Rat(24310) angiotensin I converting enzyme
  • fruit fly(41625) Acetylcholine esterase
  • Zebrafish(565980) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • chicken(419953) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • dog(610668) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Horse(100064801) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • cow(509484) angiotensin I converting enzyme
  • sheep(554335) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Domestic Rabbit(100009274) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Human ACE ELISA, for serum, plasma and cell culture supernatants,
Species
human
Mouse ACE  ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ACE1 antibody produced in rabbit, ,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Anti-Angiotensin Converting Enzyme Antibody, clone 2E2, culture supernatant, clone 2E2, from mouse,
Species Reactivity
human, rat
Application
western blot
Monoclonal Anti-CD143 antibody produced in mouse, clone 5-369,
Species Reactivity
human
Application
flow cytometry
Anti-ACE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ACE1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Lisinopril dihydrate, British Pharmacopoeia (BP) Reference Standard,
Species
human
Quinapril hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
Enalaprilat, British Pharmacopoeia (BP) Reference Standard,
Species
human
Trandolapril, British Pharmacopoeia (BP) Reference Standard,
Species
human
Quinapril Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Proteins

Product Number
Description
Species
PER1 (Hu), control peptide for AB5424P, ,
Species
human
Angiotensin Converting Enzyme from porcine kidney, lyophilized powder, ≥10 units/mg protein (Bradford),
Species

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACE, CTD-2501B8.1,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC),
Species
mouse, human, rat
Hippuryl-His-Leu acetate salt, ,
Species
mouse, human, rat
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly, ,
Species
mouse, human, rat