MilliporeSigma

CHRNB2

cholinergic receptor, nicotinic, beta 2 (neuronal)

Synonyms:
EFNL3, nAChRB2
Species:
UniProtKB ID:
Gene ID:
  • Human(1141) Summary: Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008]
  • Mouse(11444) cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
  • Rat(54239) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • dog(490443) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • naked mole-rat(101704220) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • chicken(395605) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • cow(517519) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • sheep(101104117) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • domestic guinea pig(100730761) cholinergic receptor, nicotinic, beta 2 (neuronal)
  • domestic cat(101084932) cholinergic receptor, nicotinic, beta 2 (neuronal)

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Small Molecule - Agonist

Product Number
Description
Species
(−)-Nicotine hemisulfate salt, ≥95% (TLC), ~35 % (w/v) in H2O (based on free base),
Species
human
S(−)-Nicotine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
(−)-Nicotine, PESTANAL®, analytical standard,
Species
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat

Small Molecule - Antagonist

Product Number
Description
Species
1-(4-Pyridyl)piperazine, ≥97.0% (GC),
Species
rat
Nicotinic acid, analytical standard,
Species
rat, human
Nicotinic acid, ≥98%,
Species
rat, human
Nicotinic acid, meets USP testing specifications,
Species
rat, human
Nicotinic acid, ≥99.5% (HPLC),
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHRNB2 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, pig
Application
western blot
Anti-CHRNB2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, mouse, pig
Application
western blot
Anti-CHRNB2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, pig
Application
immunohistochemistry
western blot
Anti-CHRNB2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Small Molecule - Blocker

Product Number
Description
Species
Hexamethonium chloride, solid (hygroscopic),
Species
human
Tetraethylammonium chloride, ≥98% (titration),
Species
human
Hexamethonium bromide, ,
Species
human
Kynurenic acid, ≥98%,
Species
rat, human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Chrnb2,
Species
mouse
MISSION® esiRNA, targeting human CHRNB2,
Species
human