MilliporeSigma

F2RL1

coagulation factor II (thrombin) receptor-like 1

Synonyms:
GPR11, PAR2
Species:
UniProtKB ID:
Gene ID:
  • Human(2150) Summary: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008]
  • Mouse(14063) coagulation factor II (thrombin) receptor-like 1
  • Rat(116677) coagulation factor II (thrombin) receptor-like 1
  • sheep(101106266) coagulation factor II (thrombin) receptor-like 1
  • dog(488940) coagulation factor II (thrombin) receptor-like 1
  • domestic cat(101082879) coagulation factor II (thrombin) receptor-like 1
  • cow(526525) coagulation factor II (thrombin) receptor-like 1
  • naked mole-rat(101708898) coagulation factor II (thrombin) receptor-like 1
  • domestic guinea pig(100719602) coagulation factor II (thrombin) receptor-like 1
  • chicken(427213) coagulation factor II (thrombin) receptor-like 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Proteinase-Activated Receptor 2 Antibody, NT, extracellular, Chemicon®, from rabbit,
Species Reactivity
human
Application
immunohistochemistry
Anti-PAR2 Antibody, clone 9X8E6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-Par-2 Antibody, clone SAM11, clone SAM11, from mouse,
Species Reactivity
human, mouse
Application
flow cytometry
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse F2rl1,
Species
mouse
MISSION® esiRNA, targeting human F2RL1,
Species
human