MilliporeSigma

OXT

oxytocin/neurophysin I prepropeptide

Synonyms:
OT, OT-NPI, OXT-NPI
Species:
UniProtKB ID:
Gene ID:
  • Human(5020) Summary: This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Jun 2013]
  • Mouse(18429) oxytocin
  • Rat(25504) oxytocin/neurophysin 1 prepropeptide
  • Zebrafish(352920) oxytocin
  • fruit fly(38288) peptide O-xylosyltransferase
  • cow(280888) oxytocin, prepropeptide
  • Horse(100066842) oxytocin/neurophysin I prepropeptide
  • dog(609301) oxytocin, prepropeptide
  • chicken(768516) oxytocin, prepro- (neurophysin I)
  • domestic guinea pig(100720178) oxytocin/neurophysin I prepropeptide
  • sheep(443390) oxytocin/neurophysin I prepropeptide

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Small Molecule - Antagonist

Product Number
Description
Species
Oxytocin, ,
Species
rat, human
Oxytocin, lyophilized powder, ~15 IU/mg solid (Prepared from synthetic oxytocin),
Species
rat, human
[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin, ≥93% (HPLC), solid,
Species
mouse, human
[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Et-Tyr2, Val4, Arg8]-Vasopressin, ≥97% (HPLC),
Species
mouse, rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Neurophysin 1 Antibody, clone PS 38, clone PS 38, from mouse,
Species Reactivity
rat
Application
immunohistochemistry
radioimmunoassay

western blot
Anti-OXT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Ligand

Product Number
Description
Species
Oxytocin acetate salt hydrate, ≥97% (HPLC),
Species
human

Proteins

Product Number
Description
Species
Oxytocin, ,
Species
rat, human
Oxytocin, lyophilized powder, ~15 IU/mg solid (Prepared from synthetic oxytocin),
Species
rat, human