Skip to Content
MilliporeSigma

PDCD1

programmed cell death 1

Synonyms:
CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l
Species:
UniProtKB ID:
Gene ID:
  • Human(5133) Summary: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
  • Mouse(18566) programmed cell death 1
  • Rat(301626) programmed cell death 1
  • domestic guinea pig(100721723) programmed cell death 1
  • dog(486213) programmed cell death 1
  • cow(613842) programmed cell death 1
  • naked mole-rat(101725530) programmed cell death 1
  • domestic cat(100135770) programmed cell death 1
  • sheep(101121636) programmed cell death 1
  • chicken(424913) programmed cell death 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Human PDCD1 / Programmed Cell Death Protein 1 ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-PD-1 (Tyr248) Antibody, clone 407.6G12, ,
Species Reactivity
human, monkey, mouse
Application
flow cytometry
western blot
Monoclonal Anti-CD279 PE produced in mouse, ,
Species Reactivity
Application
flow cytometry
Anti-PD-1antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM309, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-CD279-APC antibody produced in mouse, clone EH12.2H7,
Species Reactivity
Application
flow cytometry
Monoclonal Anti-CD279 antibody produced in mouse, clone EH12.2H7,
Species Reactivity
human, nonhuman primates
Application
flow cytometry

Proteins

Product Number
Description
Species
Mouse PD-1 (CD279), FC Fusion, Biotin Labeled, recombinant, expressed in HEK 293 cells,
Species
mouse
PD-1 (I134A), FC Fusion, Biotin Labeled, recombinant, expressed in HEK 293 cells,
Species
human
PD-1, FLAG® -His-Tag, Biotin Labeled, recombinant, expressed in HEK 293 cells,
Species
human
PD-1, FC Fusion, PE-Labeled, recombinant, expressed in HEK 293 cells,
Species
human
PD-1 (K78A), FC Fusion, Biotin Labeled, recombinant, expressed in HEK 293 cells,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PDCD1,
Species
human
MISSION® esiRNA, targeting mouse Pdcd1,
Species
mouse