MilliporeSigma

SLC6A2

solute carrier family 6 (neurotransmitter transporter), member 2

Synonyms:
NAT1, NET, NET1, SLC6A5
Species:
UniProtKB ID:
Gene ID:
  • Human(6530) Summary: This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(20538) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Rat(83511) solute carrier family 6 (neurotransmitter transporter), member 2
  • domestic guinea pig(100723578) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • naked mole-rat(101716834) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(101116078) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(443100) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Domestic Rabbit(100328959) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • dog(487272) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(101099605) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(493768) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Horse(100061346) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • cow(282363) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • chicken(395458) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
Description
Species
4,4′-Diaminodiphenylmethane, ≥97.0% (GC),
Species
mouse, rat
Nefazodone hydrochloride, ≥98% (HPLC), solid,
Species
human
Nefazodone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SLC6A2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-Norepinephrine Antibody, serum, Chemicon®,
Species Reactivity
human, rat
Application
immunohistochemistry
Anti-Norepinephrine Transporter Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Atomoxetine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Desipramine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Atomoxetine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Atomoxetine for impurity A identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Atomoxetine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SLC6A2,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
Bretylium tosylate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Guanethidine monosulfate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Guanethidine monosulfate, British Pharmacopoeia (BP) Reference Standard,
Species
human